Abstract
Long-term studies strongly suggest that tight control of blood glucose achieved by conventional intensive insulin treatment, self-blood glucose monitoring and patient education can significantly prevent the development and retard the progression of chronic complications of type 1 diabetes mellitus. However, the expense for this benefit was a threefold increase of the number of severe hypoglycemic episodes, a significant increase of the body weight, and dietary and other life-style restrictions affecting the quality of life
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Bretzel, R.G. (2003). Pancreatic Islet and Stem Cell Transplantation in Diabetes Mellitus: Results and Perspectives. In: Elçin, Y.M. (eds) Tissue Engineering, Stem Cells, and Gene Therapies. Advances in Experimental Medicine and Biology, vol 534. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0063-6_6
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