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Micronutrient Deficiency and Supplementation in Indonesian Infants

Effects on immune function
  • Frank T. Wieringa
  • Marjoleine A. Dijkhuizen
  • Johanna van der Ven-Ongekrijg
  • Clive E. West
  • Muhilal
  • Jos W. M. van der Meer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 531)

Abstract

Health of infants in developing countries is constantly challenged by pathogens. Unfortunately, the immune system of newborn infants is immature, developing during the first year of life to attain adequate immunocompetence at about one year of age. During the first few months of life, maternal antibodies (especially IgG) acquired in utero circulate and protect the newborn. In addition, via breast milk, the infant acquires considerable amounts of immunoglobulins (mostly sIgA) and possibly other humoral and cellular components of the mother’s immune defence. The protective effect of sIgA in breast milk is restricted to the gut. The precise role of the other immunomodulatory components of breast milk, remains unclear.

Keywords

Iron Deficiency Breast Milk Zinc Deficiency Iron Supplementation Micronutrient Deficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Frank T. Wieringa
    • 1
    • 2
    • 4
  • Marjoleine A. Dijkhuizen
    • 1
    • 2
    • 4
    • 3
  • Johanna van der Ven-Ongekrijg
    • 2
  • Clive E. West
    • 1
  • Muhilal
    • 4
  • Jos W. M. van der Meer
    • 2
  1. 1.Department of Human Nutrition and EpidemiologyWageningen UniversityThe Netherlands
  2. 2.Department of Internal MedicineUniversity Medical Center NijmegenThe Netherlands
  3. 3.Department Biology and SocietyVrije UniversityAmsterdamThe Netherlands
  4. 4.Nutrition Research and Development CentreBogorIndonesia

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