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Chemical Anatomy of the Dorsal Horn

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Abstract

Catecholamines are highly reactive compounds derived from tyrosine, which proceed via tyrosine hydroxylase (TH) to DOPA, then through DOPA decarboxylase to dopamine (DA), then through dopamine β-oxidase (DβH) to noradrenaline (NA), and finally through phenylethanolamine N-methyltransferase (PNMT) to adrenaline. These compounds have many biologic functions, for example, neurotransmitters in the sympathetic nervous system, but for spinal sensory functions they are considered in relation to nociceptive transmission.

Keywords

Dorsal Horn Vasoactive Intestinal Polypeptide Gamma Amino Butyric Acid Superficial Dorsal Horn Substantia Gelatinosa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  1. 1.The University of Texas Medical BranchGalvestonUSA

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