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General Methods for Testing Hypotheses

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Abstract

In Chapter 10 we laid out the main ideas in assessing statistical significance. First, there is a null hypothesis; second, there is a statistic that defines some deviation away from a null model; third there is a \(p\)-value to judge the rarity of the observed deviation under the null hypothesis.

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Notes

  1. 1.

    One idea is to find the “worst case” \(p\)-value (the largest) among all possible values of \(\omega \). However, this often remains intractable, except in large samples.

  2. 2.

    Fisher also pointed out that with six cups there would be only 20 permutations and thus one would at best obtain \(p=.05\); he considered this \(p\)-value too large to be useful.

  3. 3.

    Some care is required to state correctly the null hypothesis, but roughly speaking it corresponds to time intervals between post-synaptic currents being i.i.d., which they would not be if there were repeated patterns.

  4. 4.

    This is important to the logic of the mirror neuron argument. See Dinstein (2008).

  5. 5.

    We use the absolute value form \(|T_i| > c_{\alpha }\) for consistency with the two-sided tests emphasized in Chapter 10 but the logic is the same for all significance tests.

  6. 6.

    The permutations were done in source space; see Xu et al. (2011).

  7. 7.

    The null hypothesis was that for every brain source the theoretical mean activities in all movement directions were equal.

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Correspondence to Robert E. Kass .

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Kass, R.E., Eden, U.T., Brown, E.N. (2014). General Methods for Testing Hypotheses. In: Analysis of Neural Data. Springer Series in Statistics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9602-1_11

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