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Hand Function in Scleroderma

  • Angela Del RossoEmail author
  • Susanna Maddali-Bongi
  • Marco Matucci-Cerinic
Chapter

Abstract

Systemic sclerosis or scleroderma (SSc) is characterized by immunologic abnormalities, microvascular alterations, and excessive collagen production, leading to fibrosis of skin and internal organs (lungs, heart, gastrointestinal tract).

Hands are prominent targets of SSc and may be involved at different levels. Frequent signs and symptoms of the disease, such as skin and microcirculatory impairment as well as musculoskeletal involvement (of joints, tendons, and muscles), usually begin from the hands. Hand involvement evolves throughout all the course of the disease and leads to important disability in SSc.

This chapter analyzes the involvement of the hands in SSc, focusing on the causes and the kind of functional disturbances; relation between hand impairment and other clinical parameters; hand function in different stages of the disease; and tools to assess damage and function of the hand.

Keywords

Work Ability Grip Force Flexion Contracture Digital Ulcer Global Disability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Angela Del Rosso
    • 1
    Email author
  • Susanna Maddali-Bongi
    • 1
  • Marco Matucci-Cerinic
    • 1
  1. 1.Department of BioMedicine, Division of Rheumatology, Denothe Centre, Careggi Hospital (AOUC)University of FlorenceFlorenceItaly

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