Hyperchloremic Metabolic Acidosis: Nonrenal Causes
In the previous chapter, we discussed both hypo- and hyperkalemic hyperchloremic metabolic acidoses due to renal causes. In this chapter, we will discuss hypokalemic hyperchloremic metabolic acidosis due to nonrenal causes, mostly gastrointestinal (GI) disorders. Nonrenal causes of hyperchloremic metabolic acidosis are also shown. Before we discuss the pathophysiology of diarrhea, it is essential to understand water and electrolyte handling by the GI tract.
KeywordsGastrointestinal (GI) causes of hypokalemic hyperchloremic metabolic acidosis Nonrenal causes of hyperchloremic metabolic acidosis Pathophysiology of diarrhea Electrolyte composition of diarrhea Acid–base disorders in diarrhea