Though initially described by Alexander Fleming in the 1940s, there has only been a recent understanding of the development of antibacterial resistance and the role that is played by widespread antimicrobial overuse. This has spurred the development of new antimicrobials and mechanisms by which to counter microbial growth, which unfortunately has plateaued. As a result, special vigilance must now be paid to the appropriate use and timing of antimicrobials in an effort to maintain their efficacy.
KeywordsTetracycline Doxycycline Clarithromycin Fluoroquinolones Ofloxacin
- 7.Hines RL, Marschall KE. Stoelting’s anesthesia and co-existing diseases. 6th ed. Pennsylvania: Elsevier Inc.; 2012.Google Scholar
- 16.Morgan Jr GE, Mikhail MS, Murray MJ. Clinical anesthesiology. 4th ed. New York: McGraw-Hill Companies, Inc; 2006. Glucose intolerance.Google Scholar
- 22.US Department of Health and Human Services. Initial therapy for tuberculosis in the era of multidrug resistance: recommendations of the Advisory Council for the Elimination of Tuberculosis. MMWR Morb Mortal Wkly Rep. 1993;42:1–7.Google Scholar
- 23.US Department of Health and Human Services. Panel on antiretroviral guidelines for adults and adolescents. Available at http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. Section accessed 16 Mar 2013.