Abstract
Oncologic patients comprise a consistent if not significant portion of surgical patients. Many of these patients will have undergone perioperative treatment for their diseases by means of chemotherapy, radiation therapy, or a combination of the two. With regard to the chemotherapeutic agents, specific preoperative, intraoperative, and postoperative anesthetic considerations must be taken when providing care to this special subset of surgical patients.
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Anderson MR, et al. Anesthesia for patients undergoing orthopedic oncologic surgeries. J Clin Anesth. 2010;22:565–72.
Beck A, Wurch T, Bailly C, Corvaia N. Strategies and challenges for the next generation of therapeutic antibodies. Nat Rev Immunol. 2010;10(5):345–52. doi:10.1038/nri2747. PMID 20414207.
Brunton LL, et al. Goodman & Gilman’s pharmacologic basis of therapeutics. 12th ed. New York: McGraw Hill Companies; 2011.
Clowse MB, Stone JH. General toxicity of cyclophosphamide and chlorambucil in inflammatory diseases. UptoDate. 2013.
Hay JG, Haslam PL, Dewar A, et al. Development of acute lung injury after the combination of intravenous bleomycin and exposure to hyperoxia in rats. Thorax. 1987;42:374–82.
Hines RL, Marschall KE. Stoelting’s anesthesia and co-existing disease. 5th ed. Philadelphia: Churchill Livingstone; 2008.
Katsung BG, Masters SB, Trevor AJ. Basic and clinical pharmacology. 11th ed. New York: McGraw Hill Medical; 2009.
Murillo O, et al. Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies. Clin Cancer Res. 2003;9:5454–64.
NCCN Clinical Practice Guidelines in Oncology. NCCN.org: Version 1.2012 – Head and Neck Cancers; Version 1.2013 – Breast Cancer; Version 2.2012 – Acute lymphoblastic Leukemia; Version 1.2013 – Acute Myeloid Leukemia; Version 3.2013 – Chronic Myelogenous Leukemia; Version 3.2013 – Colon Cancer; Version 2.2012 – Esophageal Cancer; Version 2.2012 – Gastric Cancer; Version 4.2014 – Rectal Cancer; Version 2.2013 – Small Cell Lung Cancer; Version 2.2013 – Non-Small Cell Lung Cancer; Version 1.2012 – Testicular Cancer; Version 1.2013 – Prostate Cancer; Version 1.2013 – Ovarian Cancer, Including Fallopian Tube Cancer and Primary Peritoneal Cancer; Version 3.2012 – Uterine Neoplasms; Version 2.2012 – Cervical Cancer; Version 1.2013 – Kidney Cancer; Version 1.2013 – Central Nervous System Cancers; Version 3.2012 – Soft Tissue Sarcoma; Version 2.2013 – Bone Cancer.
Stoelting RK, Hillier SC. Pharmacology and physiology in anesthetic practice. 4th ed. Baltimore: Lippincott Williams & Wilkins; 2006. p. 551–68.
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Chemical Structures
Chemical Structure 31.1
Methotrexate(MTX)
Chemical Structure 31.2
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Warrick, A.B., Gritsenko, K., Aquino, M. (2015). Chemotherapeutic Agents. In: Kaye, A., Kaye, A., Urman, R. (eds) Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8948-1_31
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DOI: https://doi.org/10.1007/978-1-4614-8948-1_31
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