Abstract
The coordinated action of cells within the neurovascular unit is critical for proper brain functioning. Traumatic brain injury causes cell injury and death, resulting in disruptions of the intricate interactions among the surviving cells. Neurons, oligodendrocytes, astrocytes, microglia, endothelial cells, and pericytes exhibit specific responses to injury. An examination of these responses is important in understanding the pathology after brain trauma, and will be reviewed in this chapter.
Keywords
- Traumatic Brain Injury
- Diffusion Tensor Imaging
- Microglial Activation
- Reactive Astrocyte
- AQP4 Expression
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Conflict of interests: None. Funding: R37NS037074-13 (EHL), RO1NS076694-02(EHL), P01NS055104-05 (EHL), R01NS0800991-01(KA), RO1NS049430-07(KVL), RO1NS069939-02 (KVL), K08N5057339-04 (JL).
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Lok, J. et al. (2014). Neurovascular Responses to Traumatic Brain Injury. In: Lo, E., Lok, J., Ning, M., Whalen, M. (eds) Vascular Mechanisms in CNS Trauma. Springer Series in Translational Stroke Research, vol 5. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8690-9_5
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