Abstract
The morphologic assessment of ovarian masses using gray scale, 2D/3D, and color Doppler sonography has been shown to be moderately (80–90 %) accurate in distinguishing benign from malignant ovarian masses. The desire to improve the accuracy of early detection of ovarian cancer using sonography has driven to investigate the clinical application of contrast-enhanced transvaginal sonography (CE-TVS). In this chapter will be reviewed the CE-TVS as well as our experience in this field.
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References
Valentin L. Prospective cross-validation of Doppler ultrasound examination and gray-scale ultrasound imaging for discrimination of benign and malignant pelvic masses. Ultrasound Obstet Gynecol. 1999;14:273–83.
Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature. 1989;339:58–61.
Wilson SR, Greenbaum LD, Goldberg BB. Contrast-enhanced ultrasound: what is the evidence and what are the obstacles? AJR Am J Roentgenol. 2009;193:55–60.
Orden MR, Jurvelin JS, Kirkinen PP. Kinetics of a US contrast agent in benign and malignant adnexal tumors. Radiology. 2003;226:405–10.
Marret H, Sauget S, Giraudeau B, et al. Contrast enhanced sonography helps in discrimination of benign from malignant adnexal masses. J Ultrasound Med. 2004;23:1629–42.
Testa AC, Ferrandina G, Fruscella E, et al. The use of contrasted transvaginal sonography in the diagnosis of gynecologic diseases: a preliminary study. J Ultrasound Med. 2005;24:1267–78.
Fleischer AC, Lyshchik A, Jones Jr HW, et al. Contrast-enhanced transvaginal sonography of benign versus malignant ovarian masses: preliminary findings. J Ultrasound Med. 2008;27:1011–21.
Fleischer AC, Lyshchik A, Andreotti RF, et al. Advances in sonography detection of ovarian cancer: depiction of tumor neovascularity with microbubbles. AJR Am J Roentgenol. 2010;194:343–8.
Testa AC, Timmerman D, Belle VV, et al. Intravenous contrast ultrasound examination using contrast-tuned imaging (CnTITM) and the contrast medium SonoVue® for discrimination between benign and malignant adnexal masses with solid components. Ultrasound Obstet Gynecol. 2009;34:699–710.
Veyer L, Marret H, Bleuzen A, et al. Preoperative diagnosis of ovarian tumors using pelvic contrast-enhanced sonography. J Ultrasound Med. 2010;29:1041–9.
Fleischer AC, Lyshchik A, Hirari M, et al. Early detection of ovarian cancer with conventional and contrast-enhanced transvaginal sonography: recent advances and potential improvement. J Oncol. 2012;2012:302858, 11p.
Acknowledgement
This study was supported by National Institute of Health/National Cancer Institute, Grant r21 125 227–01
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Fleischer, A.C., Lyshchik, A., Fishman, D.A. (2013). Contrast-Enhanced Transvaginal Sonography of Ovarian Masses: Potential Role in Early Diagnosis of Ovarian Cancer. In: Saba, L., Acharya, U., Guerriero, S., Suri, J. (eds) Ovarian Neoplasm Imaging. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-8633-6_29
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DOI: https://doi.org/10.1007/978-1-4614-8633-6_29
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