Skip to main content

Malignant Sex Cord-Stromal Tumor: Computed Tomography and Magnetic Resonance

  • Chapter
  • First Online:
Ovarian Neoplasm Imaging
  • 1833 Accesses

Abstract

Although majority of sex cord-stromal tumor is benign, some granulosa cell tumor and Sertoli-Leydig tumors show malignant behavior. Stage is the most important prognostic factor. The recurrent sex cord-stromal tumors are usually peritoneal seeding or retroperitoneal nodule, occasionally containing intratumoral hemorrhage.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Stenwig JT, Hazekamp JT, Beecham JB. Granulosa cell tumors of the ovary. A clinicopathological study of 118 cases with long-term follow-up. Gynecol Oncol. 1979;7(2):136–52.

    Article  CAS  PubMed  Google Scholar 

  2. Gershenson DM, et al. Treatment of poor-prognosis sex cord-stromal tumors of the ovary with the combination of bleomycin, etoposide, and cisplatin. Obstet Gynecol. 1996;87(4):527–31.

    Article  CAS  PubMed  Google Scholar 

  3. Surratt JT, Siegel MJ. Imaging of pediatric ovarian masses. Radiographics. 1991;11(4):533–48.

    Article  CAS  PubMed  Google Scholar 

  4. Schumer ST, Cannistra SA. Granulosa cell tumor of the ovary. J Clin Oncol. 2003;21(6):1180–9.

    Article  PubMed  Google Scholar 

  5. Malmstrom H, et al. Granulosa cell tumors of the ovary: prognostic factors and outcome. Gynecol Oncol. 1994;52(1):50–5.

    Article  CAS  PubMed  Google Scholar 

  6. Miller BE, et al. Prognostic factors in adult granulosa cell tumor of the ovary. Cancer. 1997;79(10):1951–5.

    Article  CAS  PubMed  Google Scholar 

  7. Fox H, Agrawal K, Langley FA. A clinicopathologic study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis. Cancer. 1975;35(1):231–41.

    Article  CAS  PubMed  Google Scholar 

  8. Evans 3rd AT, et al. Clinicopathologic review of 118 granulosa and 82 theca cell tumors. Obstet Gynecol. 1980;55(2):231–8.

    PubMed  Google Scholar 

  9. Costa MJ, et al. Immunohistochemical phenotype of ovarian granulosa cell tumors: absence of epithelial membrane antigen has diagnostic value. Hum Pathol. 1994;25(1):60–6.

    Article  CAS  PubMed  Google Scholar 

  10. Fujimoto T, et al. Histopathological prognostic factors of adult granulosa cell tumors of the ovary. Acta Obstet Gynecol Scand. 2001;80(11):1069–74.

    Article  CAS  PubMed  Google Scholar 

  11. Morikawa K, et al. Granulosa cell tumor of the ovary: MR findings. J Comput Assist Tomogr. 1997;21(6):1001–4.

    Article  CAS  PubMed  Google Scholar 

  12. Outwater EK, et al. Sex cord-stromal and steroid cell tumors of the ovary. Radiographics. 1998;18(6):1523–46.

    Article  CAS  PubMed  Google Scholar 

  13. Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases. Am J Surg Pathol. 1985;9(8):543–69.

    Article  CAS  PubMed  Google Scholar 

  14. Roth LM, et al. Sertoli-Leydig cell tumors: a clinicopathologic study of 34 cases. Cancer. 1981;48(1):187–97.

    Article  CAS  PubMed  Google Scholar 

  15. Zaloudek C, Norris HJ. Sertoli-Leydig tumors of the ovary. A clinicopathologic study of 64 intermediate and poorly differentiated neoplasms. Am J Surg Pathol. 1984;8(6):405–18.

    Article  CAS  PubMed  Google Scholar 

  16. Prat J, Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors with heterologous elements. II. Cartilage and skeletal muscle: a clinicopathologic analysis of twelve cases. Cancer. 1982;50(11):2465–75.

    Article  CAS  PubMed  Google Scholar 

  17. Rha SE, et al. Recurrent ovarian granulosa cell tumors: clinical and imaging features. Abdom Imaging. 2008;33(1):119–25.

    Article  PubMed  Google Scholar 

  18. Brown J, et al. Patterns of metastasis in sex cord-stromal tumors of the ovary: can routine staging lymphadenectomy be omitted? Gynecol Oncol. 2009;113(1):86–90.

    Article  PubMed  Google Scholar 

Download references

Acknowledgement

I would like to acknowledge Prof. M. Kataoka in Dept. of Diagnostic Radiology, Kyoto University, for her great help to find CT images and clinical information of patients with recurrent granulosa cell tumor.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Takashi Koyama MD, PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this chapter

Cite this chapter

Koyama, T. (2013). Malignant Sex Cord-Stromal Tumor: Computed Tomography and Magnetic Resonance. In: Saba, L., Acharya, U., Guerriero, S., Suri, J. (eds) Ovarian Neoplasm Imaging. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-8633-6_19

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-8633-6_19

  • Published:

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4614-8632-9

  • Online ISBN: 978-1-4614-8633-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics