Abstract
Asthma involves variable airflow obstruction in both large and small airways. The physiological consequences of obstruction include increased airway resistance and decreased expiratory flow rates, which lead to air trapping and dynamic hyperinflation. This chapter reviews current methods for pulmonary function testing to detect these physiological changes for both diagnosis and monitoring.
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References
Adams RJ, Boath K, Homan S et al (2001) A randomized trial of peak-flow and symptom-based action plans in adults with moderate-to-severe asthma. Respirology 6:297–304
Alberts WM, Ferris MC, Brooks SM et al (1994) The FEF25-75% and the clinical diagnosis of asthma. Ann Allergy 73:221–225
Argyros GJ, Roach JM, Hurwitz KM et al (1996) Eucapnic voluntary hyperventilation as a bronchoprovocation technique: development of a standardized dosing schedule in asthmatics. Chest 109:1520–1524
Buist AS, Vollmer WM, Wilson SR et al (2006) A randomized clinical trial of peak flow versus symptom monitoring in older adults with asthma. Am J Respir Crit Care Med 174:1077–1087
Collard P, Njinou B, Nejadnik B et al (1994) Single breath diffusing capacity for carbon monoxide in stable asthma. Chest 105:1426–1429
Drewek R, Garber E, Stanclik S et al (2009) The FEF25-75 and its decline as a predictor of methacholine responsiveness in children. J Asthma 46:375–381
Ferris BG (1978) Epidemiology standardization project (American Thoracic Society). Am Rev Respir Dis 118:1–120
Hansen JE, Sun XG, Wasserman K (2007) Spirometric criteria for airway obstruction: Use percentage of FEV1/FVC ratio below the fifth percentile, not < 70%. Chest 131:349–355
Henderson JC, O’Connell F, Fuller RW (1993) Decrease of histamine induced bronchoconstriction by caffeine in mild asthma. Thorax 48:824–826
Holley AB, Cohee B, Walter RJ et al (2012) Eucapnic voluntary hyperventilation is superior to methacholine challenge testing for detecting airway hyperreactivity in nonathletes. J Asthma 49:614–619
Keens TG, Mansell A, Krastins IR et al (1979) Evaluation of the single-breath diffusing capacity in asthma and cystic fibrosis. Chest 76:41–44
McGrath KW, Fahy JV (2011) Negative methacholine challenge tests in subjects who report physician-diagnosed asthma. Clin Exp Allergy 41:46–51
NAEPP (2007) National Asthma Education and Prevention Program TEPotDaMoA. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. National Heart, Lung, and Blood Institute, Bethesda, MD
Russell NJ, Crichton NJ, Emerson PA et al (1986) Quantitative assessment of the value of spirometry. Thorax 41:360–363
Scott S, Currie J, Albert P et al (2012) Risk of misdiagnosis, health-related quality of life, and BMI in patients who are overweight with doctor-diagnosed asthma. Chest 141:616–624
Turner MO, Taylor D, Bennett R et al (1998) A randomized trial comparing peak expiratory flow and symptom self-management plans for patients with asthma attending a primary care clinic. Am J Respir Crit Care Med 157:540–546
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Shah, S., Sharma, G. (2014). Current Clinical Diagnostic Tests for Asthma. In: Brasier, A. (eds) Heterogeneity in Asthma. Advances in Experimental Medicine and Biology, vol 795. Humana Press, Boston, MA. https://doi.org/10.1007/978-1-4614-8603-9_5
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DOI: https://doi.org/10.1007/978-1-4614-8603-9_5
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