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Closed-Loop Anesthesia Based on Neuromonitoring

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Monitoring Technologies in Acute Care Environments

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Abstract

This chapter reviews clinical studies concerning the automated administration of anesthetic agents guided by electrocortical activity. Studies have demonstrated the feasibility of automated control of propofol guided by the Bispectral Index for general anesthesia induction and maintenance. Automated control of propofol has been shown to outperform manual control and can be used for major surgery. At present, dual closed-loop control of propofol-remifentanil guided by Bispectral Index or Entropy is under evaluation. The automated titration of anesthetic drugs is no longer an esoteric research tool – it is now a tool for the clinicians of the future.

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, Hôpital Foch and Outcomes Research Consortium, 40 rue Worth, Suresnes, 92151, France

    Ngai Liu MD, PhD

  2. Anesthésie – Réanimation Chirurgicale, Hôpital Tenon, 4 rue de la Chine, Paris, 75020, France

    El Medhi Hafiani MD

  3. Department of Anesthesiology, Hopital Foch, 40 rue Worth, Suresnes, 92151, France

    Morgan Le Guen MD

Authors
  1. Ngai Liu MD, PhD
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  2. El Medhi Hafiani MD
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  3. Morgan Le Guen MD
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Corresponding author

Correspondence to Ngai Liu MD, PhD .

Editor information

Editors and Affiliations

  1. Departments of Anesthesiology, Surgery, and Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

    Jesse M. Ehrenfeld

  2. Department of Anesthesiology and Perioperative Care, University of California, Irvine, Irvine, California, USA

    Maxime Cannesson

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Liu, N., Hafiani, E.M., Le Guen, M. (2014). Closed-Loop Anesthesia Based on Neuromonitoring. In: Ehrenfeld, J., Cannesson, M. (eds) Monitoring Technologies in Acute Care Environments. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8557-5_33

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  • DOI: https://doi.org/10.1007/978-1-4614-8557-5_33

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-8556-8

  • Online ISBN: 978-1-4614-8557-5

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