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Hematologic Changes with Aging

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Geriatric Trauma and Critical Care

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Abstract

The age-related hematologic changes of older trauma victims include a baseline anemia and hypercoagulability. These patients have less responsive bone marrow and are slower to repopulate cell lines following injury and hemorrhage. Pre-injury medication profiles for older patients will often include at least one anticoagulant, and understanding of its mechanism and reversal can be lifesaving. The geriatric trauma patient is challenging, and knowledge of both natural and iatrogenic hematologic changes is paramount to their care.

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Authors and Affiliations

  1. Department of Surgery, Carolinas Medical Center, 1000 Blythe Blvd., MEB 6, Charlotte, NC, 28203, USA

    Peter E. Fischer MD, MS

  2. Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L611, Portland, OR, 97239, USA

    Thomas G. DeLoughery MD

  3. Department of Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L611, Portland, OR, 97239, USA

    Martin A. Schreiber MD, FACS

Authors
  1. Peter E. Fischer MD, MS
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  2. Thomas G. DeLoughery MD
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  3. Martin A. Schreiber MD, FACS
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Correspondence to Peter E. Fischer MD, MS .

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Editors and Affiliations

  1. Department of Surgery, Lincoln Medical Center, Bronx, New York, USA

    Jay A. Yelon

  2. Department of Surgery, Stritch School of Medicine, Loyola University Medical Center, Maywood, Illinois, USA

    Fred A. Luchette

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Fischer, P.E., DeLoughery, T.G., Schreiber, M.A. (2014). Hematologic Changes with Aging. In: Yelon, J., Luchette, F. (eds) Geriatric Trauma and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8501-8_7

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  • DOI: https://doi.org/10.1007/978-1-4614-8501-8_7

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