Colorectal Cancer: Metastatic (Palliation)

  • Elisabeth C. McLemore
  • Sonia Ramamoorthy


  • Approximately 20 % of colorectal cancer patients present with established distant metastases. A diagnosis of stage IV disease allows for appropriate operative and oncologic planning.

  • Among these patients there is enormous heterogeneity with respect to sites of disease, extent of disease, symptoms, performance status, and comorbidities. The clinical spectrum at the time of diagnosis ranges from the asymptomatic patient with a single metastatic lesion to the rapidly deteriorating patient with colon obstruction and advanced, multiorgan metastases.

  • While treatment algorithms may exist for some forms of metastatic disease such as a solitary liver lesion, others are still being defined.


Colorectal Cancer Rectal Cancer Brain Metastasis Liver Resection Systemic Chemotherapy 
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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Colon and Rectal SurgeryUniversity of California, San Diego Medical Center/Moores Cancer CenterLa JollaUSA
  2. 2.Department of Colon and Rectal SurgeryUniversity of California, San Diego Medical Center/Rebecca and John Moores Cancer CenterLa JollaUSA

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