IBD: Diagnosis and Evaluation



  • In 1932, Crohn, Ginzburg, and Oppenheimer described 13 patients with “regional ileitis.”

  • It was their published description that established the formal classification of the disease syndrome and association with noncaseating granulomas.

  • The surgeon involved in the care of the majority of the patients, Dr. AA Berg, did not want his name included in the article.

  • Brooke and Lockhart-Mummery pointed out both the segmental and granulomatous nature of the colitis in CD.

  • Brooke contributed significantly by introducing pioneering surgical techniques in the 1950s that created a more functional ileostomy.

  • Truelove and Witts in 1959 reported on a double-blind, controlled study demonstrating the value of high-dose cortisone as treatment for severe colitis.

  • The ileal pouch anal anastomosis (IPAA) was first described by Parks and Nicholls in 1978 and subsequently refined by Utsunomiya.

  • The IPAA is now the standard of care for the surgical correction of UC.


Osteoporosis Diarrhea Psoriasis Perforation Constipation 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Division of Colon and Rectal Surgery, Department of SurgeryPenn State Milton S. Hershey Medical CenterHersheyUSA

Personalised recommendations