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The iStent® MIGS Family: iStent®, iStent Inject®, and iStent Supra®

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Book cover Surgical Innovations in Glaucoma

Abstract

Microinvasive glaucoma surgeries or MIGS, an acronym coined by Ike Ahmed, represents a fundamental shift in glaucoma surgical philosophy. MIGS exploit existing physiologic outflow pathways allowing both rapid placement and visual recovery. The surgeon interacts with small anatomic functional structures in a minimally destructive manner. The first two Glaukos devices target trabecular outflow (iStenttm (G1) and iStenttm inject (G2)). The third targets uveoscleral outflow (iStenttm Supra (G3)). Theoretical modeling and ex vivo studies were used to study changes in trabecular outflow facility with multiple trabecular stents. This question is being studied clinically and 4000 iStentstm of all types in total have been placed in over 30 studies over the past 10 years. Two trabecular or two uveal scleral stents seem most favorable in terms of risks, costs, and effectiveness. There is also some advantage to using both trabecular and uveal scleral stents in eyes requiring lower target pressures.

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Author information

Authors and Affiliations

  1. Orange County Glaucoma Inc., 1200 N. Tustin Ave, S. 240, Santa Anna, CA, 92705, USA

    Richard A. Hill MD

  2. Product Development, Glaukos Corp., 26051 Merit Circle, Suite 103, Laguna Hills, CA, 92653, USA

    David Haffner (Vice President)

  3. Glaucoma, S.V. Malayan Eye Center, Fuchik’s Street, 30, Orbbii Street; 4; app. 55, Yerevan, Arabkir, 375028, Armenia

    Lilit Voskanyan MD, PhD

Authors
  1. Richard A. Hill MD
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  2. David Haffner
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  3. Lilit Voskanyan MD, PhD
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Corresponding author

Correspondence to Richard A. Hill MD .

Editor information

Editors and Affiliations

  1. Department of Surgery, Rocky Vista University, Parker, CO, USA

    John R. Samples MD

  2. Western Glaucoma Foundation, Portland, OR, USA

    John R. Samples MD

  3. Cornea Consultants of Colorado, Littleton, CO, USA

    John R. Samples MD

  4. The Eye Clinic, Portland, OR, USA

    John R. Samples MD

  5. Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada

    Iqbal Ike K. Ahmed MD, FRCSC

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Hill, R.A., Haffner, D., Voskanyan, L. (2014). The iStent® MIGS Family: iStent®, iStent Inject®, and iStent Supra®. In: Samples, J.R., Ahmed, I.I.K. (eds) Surgical Innovations in Glaucoma. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8348-9_13

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  • DOI: https://doi.org/10.1007/978-1-4614-8348-9_13

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-8347-2

  • Online ISBN: 978-1-4614-8348-9

  • eBook Packages: MedicineMedicine (R0)

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