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Perioral Dermatitis

  • Bryan Gammon
  • Bethanee J. Schlosser
Chapter

Abstract

Perioral dermatitis (PD), a common acneiform facial eruption, was first described in the 1950s. The terms “light-sensitive seborrheid” and “steroid-induced rosacea-like dermatitis” were previously used to describe this condition [1, 2]. Given the now recognized periorbital, perinasal, and perioral distribution of lesions, the term periorificial dermatitis may be most appropriate [3].

Keywords

Topical Corticosteroid Allergic Contact Dermatitis Azelaic Acid Erythematous Papule Oral Tetracycline 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Frumess GM, Lewis HM. Light-sensitive seborrheid. AMA Arch Dermatol. 1957; 75(2):245–8.CrossRefGoogle Scholar
  2. 2.
    Mihan R, Ayres Jr S. Perioral dermatitis. Arch Dermatol. 1964;89:803–5.PubMedCrossRefGoogle Scholar
  3. 3.
    Kihiczak GG, Cruz MA, Schwartz RA. Periorificial dermatitis in children: an update and description of a child with striking features. Int J Dermatol. 2009;48(3):304–6.PubMedCrossRefGoogle Scholar
  4. 4.
    Hafeez ZH. Perioral dermatitis: an update. Int J Dermatol. 2003;42(7):514–7.PubMedCrossRefGoogle Scholar
  5. 5.
    Dubus JC, Marguet C, Deschildre A, et al. Local side-effects of inhaled corticosteroids in asthmatic children: influence of drug, dose, age, and device. Allergy. 2001;56(10):944–8.PubMedCrossRefGoogle Scholar
  6. 6.
    Poulos GA, Brodell RT. Perioral dermatitis associated with an inhaled corticosteroid. Arch Dermatol. 2007;143(11):1460.PubMedCrossRefGoogle Scholar
  7. 7.
    Adams SJ, Davison AM, Cunliffe WJ, Giles GR. Perioral dermatitis in renal transplant recipients maintained on corticosteroids and immunosuppressive therapy. Br J Dermatol. 1982;106(5):589–92.PubMedCrossRefGoogle Scholar
  8. 8.
    Clementson B, Smidt AC. Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. Pediatr Dermatol. 2012;29(3):331–2.PubMedCrossRefGoogle Scholar
  9. 9.
    Wilkinson DS, Kirton V, Wilkinson JD. Perioral dermatitis: a 12-year review. Br J Dermatol. 1979;101(3):245–57.PubMedCrossRefGoogle Scholar
  10. 10.
    Nguyen V, Eichenfield LF. Periorificial dermatitis in children and adolescents. J Am Acad Dermatol. 2006;55(5):781–5.PubMedCrossRefGoogle Scholar
  11. 11.
    Weston WL, Morelli JG. Identical twins with perioral dermatitis. Pediatr Dermatol. 1998;15(2):144.PubMedCrossRefGoogle Scholar
  12. 12.
    Nedorost ST. Medical pearl—the evaluation of perioral dermatitis: use of an extended patch test series. J Am Acad Dermatol. 2007;56(5 Suppl):S100–2.PubMedCrossRefGoogle Scholar
  13. 13.
    Arutjunow V. Perioral dermatitis—an allergic disease? Hautarzt. 1978;29(2):89–91.PubMedGoogle Scholar
  14. 14.
    Bradford LG, Montes LF. Perioral dermatitis and Candida albicans. Arch Dermatol. 1972; 105(6):892–5.PubMedCrossRefGoogle Scholar
  15. 15.
    Hsu CK, Hsu MM, Lee JY. Demodicosis: a clinicopathological study. J Am Acad Dermatol. 2009;60(3):453–62.PubMedCrossRefGoogle Scholar
  16. 16.
    Hogan DJ. Perioral dermatitis. Curr Probl Dermatol. 1995;22:98–104.PubMedGoogle Scholar
  17. 17.
    Urbatsch AJ, Frieden I, Williams ML, Elewski BE, Mancini AJ, Paller AS. Extrafacial and generalized granulomatous periorificial dermatitis. Arch Dermatol. 2002;138(10):1354–8.PubMedCrossRefGoogle Scholar
  18. 18.
    Hall CS, Reichenberg J. Evidence based review of perioral dermatitis therapy. G Ital Dermatol Venereol. 2010;145(4):433–44.PubMedGoogle Scholar
  19. 19.
    Weber K, Thurmayr R. Critical appraisal of reports on the treatment of perioral dermatitis. Dermatology. 2005;210(4):300–7.PubMedCrossRefGoogle Scholar
  20. 20.
    Miller SR, Shalita AR. Topical metronidazole gel (0.75%) for the treatment of perioral dermatitis in children. J Am Acad Dermatol. 1994;31(5 Pt 2):847–8.PubMedCrossRefGoogle Scholar
  21. 21.
    Veien NK, Munkvad JM, Nielsen AO, Niordson AM, Stahl D, Thormann J. Topical metronidazole in the treatment of perioral dermatitis. J Am Acad Dermatol. 1991;24(2 Pt 1):258–60.PubMedCrossRefGoogle Scholar
  22. 22.
    Bikowski JB. Topical therapy for perioral dermatitis. Cutis. 1983;31(6):678–82.PubMedGoogle Scholar
  23. 23.
    Weber K, Thurmayr R, Meisinger A. A topical erythromycin preparation and oral tetracycline for the treatment of perioral dermatitis: a placebo-controlled trial. J Dermatol Treat. 1993; 4:57–9.CrossRefGoogle Scholar
  24. 24.
    Weber K. How I, treat perioral dermatitis: non-compliance with the treatment guidelines. Dermatology. 2003;207(2):215.PubMedCrossRefGoogle Scholar
  25. 25.
    Oppel T, Pavicic T, Kamann S, Brautigam M, Wollenberg A. Pimecrolimus cream (1%) efficacy in perioral dermatitis—results of a randomized, double-blind, vehicle-controlled study in 40 patients. J Eur Acad Dermatol Venereol. 2007;21(9):1175–80.PubMedGoogle Scholar
  26. 26.
    Schwarz T, Kreiselmaier I, Bieber T, et al. A randomized, double-blind, vehicle-controlled study of 1% pimecrolimus cream in adult patients with perioral dermatitis. J Am Acad Dermatol. 2008;59(1):34–40.PubMedCrossRefGoogle Scholar
  27. 27.
    Macdonald A, Feiwel M. Perioral dermatitis: aetiology and treatment with tetracycline. Br J Dermatol. 1972;87(4):315–9.PubMedCrossRefGoogle Scholar
  28. 28.
    Misago N, Nakafusa J, Narisawa Y. Childhood granulomatous periorificial dermatitis: lupus miliaris disseminatus faciei in children? J Eur Acad Dermatol Venereol. 2005;19(4):470–3.PubMedCrossRefGoogle Scholar
  29. 29.
    Rosso JQ. Management of papulopustular rosacea and perioral dermatitis with emphasis on iatrogenic causation or exacerbation of inflammatory facial dermatoses: use of doxycycline-modified release 40mg capsule once daily in combination with properly selected skin care as an effective therapeutic approach. J Clin Aesthet Dermatol. 2011;4(8):20–30.PubMedGoogle Scholar
  30. 30.
    Jansen T. Azelaic acid as a new treatment for perioral dermatitis: results from an open study. Br J Dermatol. 2004;151(4):933–4.PubMedCrossRefGoogle Scholar
  31. 31.
    Jansen T, Melnik BC, Schadendorf D. Steroid-induced periorificial dermatitis in children–clinical features and response to azelaic acid. Pediatr Dermatol. 2010;27(2):137–42.PubMedCrossRefGoogle Scholar
  32. 32.
    Richey DF, Hopson B. Photodynamic therapy for perioral dermatitis. J Drugs Dermatol. 2006;5(2 Suppl):12–6.PubMedGoogle Scholar
  33. 33.
    Bendl BJ. Perioral dermatitis: etiology and treatment. Cutis. 1976;17(5):903–8.PubMedGoogle Scholar
  34. 34.
    Jansen T. Perioral dermatitis successfully treated with topical adapalene. J Eur Acad Dermatol Venereol. 2002;16(2):175–7.PubMedCrossRefGoogle Scholar
  35. 35.
    Smith KW. Perioral dermatitis with histopathologic features of granulomatous rosacea: successful treatment with isotretinoin. Cutis. 1990;46(5):413–5.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Bryan Gammon
    • 1
  • Bethanee J. Schlosser
    • 1
  1. 1.Department of DermatologyNorthwestern UniversityChicagoUSA

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