Abstract
Raynaud’s phenomenon presents clinically as cold mottled skin and most commonly involves the extremities. It results from vasoconstriction of the superficial thermoregulatory vessels as an exaggerated response to cold temperatures and/or to stress. It can occur primarily, without an associated autoimmune disease, or can relate to underlying rheumatic diseases such as scleroderma or mixed connective tissue disease.
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Sherber, N.S., Wigley, F.M. (2014). Skin Manifestations of Raynaud’s Phenomenon. In: Matucci-Cerinic, M., Furst, D., Fiorentino, D. (eds) Skin Manifestations in Rheumatic Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7849-2_23
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DOI: https://doi.org/10.1007/978-1-4614-7849-2_23
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