Skin Manifestations of Raynaud’s Phenomenon

  • Noëlle S. SherberEmail author
  • Fredrick M. Wigley


Raynaud’s phenomenon presents clinically as cold mottled skin and most commonly involves the extremities. It results from vasoconstriction of the superficial thermoregulatory vessels as an exaggerated response to cold temperatures and/or to stress. It can occur primarily, without an associated autoimmune disease, or can relate to underlying rheumatic diseases such as scleroderma or mixed connective tissue disease.


Carpal Tunnel Syndrome Mixed Connective Tissue Disease Thoracic Outlet Syndrome Digital Artery Undifferentiated Connective Tissue Disease 
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Suggested Readings

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Copyright information

© Springer Science+Business Media, LLC 2014

Authors and Affiliations

  1. 1.Johns Hopkins Scleroderma CenterBaltimoreUSA
  2. 2.Division of RheumatologyJohns Hopkins University School of MedicineBaltimoreUSA

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