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Translating Stem Cell Discoveries

Chapter

Abstract

Stem cells are moving rapidly in translation and into clinical trials. Those based on sound scientific data will eventually dominate the clinical spectrum of new therapeutics. Presently there are many studies that do not show significant and repeatable efficacy in the larger cohorts of patients that may be due to the lack of rigor in determining the basic mechanism of action of the cellular therapy. Drawing together academic, clinical, and company interests in a new modality of using stem cells as therapeutics is helpful for addressing difficult issues arising, enables deeper infrastructure, provides focus in meeting the demands of translation for trial registration and targets ensure that clinical relevance is addressed. The demands of translation and the costs of studies required mean that both public and private finance is needed. As an example, CIRM (California Institute for Regenerative Medicine) has a large portfolio of projects with private partnerships that are increasing the potential clinical opportunities for many diseases and injuries with little treatment currently available. With this increasing pressure for clinical trials, new approaches are needed for networked clinical facilities in the tertiary medical institutions. The translation of primary stem cell discoveries has considerable momentum and likely to provide many new therapies and cures for a wide spectrum of conditions.

Keywords

Stem Cell Amyotrophic Lateral Sclerosis Mesenchymal Stem Cell Neural Stem Cell Stem Cell Research 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science + Business Media New York 2013

Authors and Affiliations

  1. 1.California Institute for Regenerative MedicineSan FranciscoUSA

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