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Systems Biology of Population Cell Response

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Immuno Systems Biology

Part of the book series: Systems Biology ((SYSTBIOL,volume 3))

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Abstract

Living organisms are well known to survive, adapt, and even reproduce under adverse or challenging conditions. The ability to handle diverse environmental changes or perturbations is inherent to the large repertoire of genes, proteins, and metabolites that interact in response to external cues. The detection of extracellular or intracellular signals is channeled through molecular networks within and between cells, resulting in dynamic responses that process and disseminate information for necessary biological action, collectively, at an organismal level. The formation of biofilms, or cellular structures, through the aggregation and adhering of cells with one another, by bacteria to enhance individual survivability to environmental attacks is a good example of interactive and adaptive behavior in biology. Mechanistically, how do living systems self-organize to achieve their purpose to survive?

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Authors and Affiliations

  1. Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan

    Kumar Selvarajoo

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  1. Kumar Selvarajoo
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Selvarajoo, K. (2013). Systems Biology of Population Cell Response. In: Immuno Systems Biology. Systems Biology, vol 3. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7690-0_1

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