Optical Navigation

  • Ichiro Sakuma


Optical measurement has been widely used for obtaining physiological and biochemical information used for intra-operative diagnosis. Optical signals such as tissue reflectance spectra and fluorescence spectra of endogenous or exogenous fluorescent molecules that provide pathological information can be used for identification of pathological lesion during surgical operation. These kinds of optical information can be mapped to the anatomical information used for surgical navigation to help surgeon’s intra-operative determination of pathological/healthy area in surgical field. This enables target therapy of the pathological area that can keep the healthy tissue intact. Appropriate use of molecular probes that serve as contrast agent for specific target is important. Since optical information provides only the information from surface layer of the tissue because penetration depth of light is limited due to tissue absorption and scattering, integration with other volumetric information obtained by three dimensional medical imaging systems such as CT and MRI is recommended to realize practical surgical navigation system.


Sentinel Lymph Node Moyamoya Disease Superficial Temporal Artery Surgical Navigation Residual Tumor Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Medical Device Development and Regulation Research Center, Department of Bioengineering and Department of Precision Engineering, School of EngineeringThe University of TokyoTokyoJapan

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