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Clinical Physiology of Sleep pp 199–220Cite as

Homeostasis and Heteroplasticity: Functional Significance of Behavioral State Sequences

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Abstract

if energy and information are separable physical domains in which physiological systems evolve, how can we conceptualize the rules that govern physiological adaptation? For many years the reigning research paradigm in physiology has been that of homeostasis. Enunciated by Claude Bernard (6) as “constancy of the internal milieu” and articulated by Walter B. Cannon (11) in The Wisdom of the Body, the concept of homeostasis emphasized conservative and energetic aspects of adaptation: constancy was the goal 199 and the role of physiological systems was to adjust to environmental change so as to maintain equilibrium. The homeostasis concept was compatible with the reflex paradigm of Sherringtonian neurobiology and has successfully guided experimentation on sensorimotor systems for a century.

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Author information

Authors and Affiliations

  1. Laboratory of Neurophysiology, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA

    J. Allan Hobson

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  1. J. Allan Hobson
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Editors and Affiliations

  1. Departments of Medicine and Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA

    Ralph Lydic

  2. Department of Anesthesia, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA

    Julien F. Biebuyck

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© 1988 American Physiological Society

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Hobson, J.A. (1988). Homeostasis and Heteroplasticity: Functional Significance of Behavioral State Sequences. In: Lydic, R., Biebuyck, J.F. (eds) Clinical Physiology of Sleep. Clinical Physiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7599-6_14

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  • DOI: https://doi.org/10.1007/978-1-4614-7599-6_14

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7599-6

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