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Central Regulation of Sleep and Autonomic Physiology

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Clinical Physiology of Sleep

Part of the book series: Clinical Physiology ((CLINPHY))

Abstract

the loss of wakefulness, or the onset of sleep, causes significant changes in the central regulation of autonomic function. Because of the global nature of these state-dependent changes in neural control, the output of many organ systems is altered during sleep. The fact that multiple organ systems may be simultaneously affected by changes in states of consciousness underscores the potential clinical relevance of these sleep-dependent changes in physiology. Recognition of this relevance has spawned the development of a new clinical subspeciality (31, 50, 53) referred to by some as sleep-disorders medicine (19). In addition to sleep disorders per se (52), considerable evidence documents cardiovascular (16, 57; see chapters 3 and 5 in this volume) and respiratory (10; see chapters 7 and 8 in this volume) disorders that occur during sleep. The chapters comprising this volume illustrate both the widespread nature of sleep-dependent changes in physiology and the potential relevance of these physiological changes for clinical medicine. This chapter briefly outlines some of the conceptual and historical factors that have contributed to the cellular study of sleep-dependent changes in central autonomic control. The purpose of the present chapter is to introduce this volume by illustrating an investigative approach that seeks to unify cellular level analyses with integrative physiology.

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Authors and Affiliations

  1. Departments of Medicine and Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA

    Ralph Lydic

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  1. Ralph Lydic
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Editors and Affiliations

  1. Departments of Medicine and Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA

    Ralph Lydic

  2. Department of Anesthesia, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA

    Julien F. Biebuyck

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© 1988 American Physiological Society

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Lydic, R. (1988). Central Regulation of Sleep and Autonomic Physiology. In: Lydic, R., Biebuyck, J.F. (eds) Clinical Physiology of Sleep. Clinical Physiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7599-6_1

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  • DOI: https://doi.org/10.1007/978-1-4614-7599-6_1

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7599-6

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