Characteristics of Prehypertension in Black Children

  • Bonita Falkner
Part of the Clinical Physiology Series book series (CLINPHY)


Hypertension is a leading health problem in the United States and in other countries. Epidemiological studies have demonstrated racial and geographical differences in prevalence for essential hypertension (EH). In the United States, blacks have a greater prevalence of EH (10,72). This difference is further accentuated by vital statistics data on mortality. Blacks have a threefold greater mortality from hypertensive disease than whites. This disproportionate mortality rises to more than six times greater in blacks in the age range 35–54 years (87). Thus, the morbid consequences of hypertensive disease are severalfold greater in blacks, particularly in young adulthood and mid-adulthood (35).


Insulin Resistance Essential Hypertension Blood Pressure Response Cardiovascular Reactivity Black Child 
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  1. 1.
    Abramson, E. A., and R. A. Arky. Role of beta adrenergic receptors in counter regulation to insulin-induced hyperglycemia. Diabetes 17: 141 - 146, 1968.PubMedGoogle Scholar
  2. 2.
    Anderson, N. B., J. D. Lane, M. Muranka, R. B. Williams, and S. J. Houseworth. Racial differences in blood pressure and forearm vascular responses to the cold face stimulus. Psychosom. Med. 50: 57 - 63, 1988.PubMedGoogle Scholar
  3. 3.
    Baumann, R., H. Ziprian, W. Godicke, W. Hartrodt, E. Naumann, and J. Lauter. The influence of acute psychic stress situations and vegetative parameters of essential hypertensives at the early stage of the disease. Psychother. Psychosom. 22: 131 - 137, 1973.PubMedCrossRefGoogle Scholar
  4. 4.
    Berglund, G., B. Larsson, O. Anderson, O. Larsson, K. Svardsudd, P. Bjorntorp, and L. Wilhelmsen. Body composition and glucose metabolism in hypertensive middle-aged males. Acta Med. Scand. 200: 163 - 169, 1976.PubMedCrossRefGoogle Scholar
  5. 5.
    Bucher, H., J. Zapf, T. Torresani, A. Prader, E. R. Froesch, and R. Illig. Insulin-like growth factors I and II, prolactin, and insulin in 19 growth hormone-deficient children with excessive, normal, or decreased growth after operation for craniopharyngioma. N. Engl. J. Med. 309: 1142 - 1146, 1983.PubMedCrossRefGoogle Scholar
  6. 6.
    Burke, G. L., D. S. Freedman, L. S. Webber, and G. S. Berenson. Persistence of high diastolic blood pressure in thin children. The Bogalusa Heart Study. Hypertension 8: 2429, 1986.CrossRefGoogle Scholar
  7. 7.
    Burke, G. L., L. S. Webber, S. R. Srinivasan, B. Radhakrishnamurthy, D. S. Freedman, and G. S. Berenson. Fasting plasma glucose and insulin levels and their relationship to cardiovascular risk factors in children: the Bogalusa Heart Study. Metabolism 35: 44 1446, 1986.Google Scholar
  8. 8.
    Clarke, W. R., R. F. Woolson, and R. M. Lauer. Changes in ponderosity and blood pressure in childhood: the Muscatine Study. Am. J. Epidemiol. 124: 195 - 206, 1986.PubMedGoogle Scholar
  9. 9.
    Clemmon, D. R., and J. J. Van Wyk. Evidence for a functional role of endogenously produced somatomedin-like peptides in the regulation of DNA synthesis in cultured human fibroblasts and porcine smooth muscle cells. J. Clin. Invest. 75: 1914 - 1918, 1985.CrossRefGoogle Scholar
  10. 10.
    Comstock, G. W. An epidemiologic study of blood pressure levels in a bi-racial community in the Southern United States. Am. J. Hyg. 65: 271 - 278, 1957.Google Scholar
  11. 11.
    Cornoni-Huntley, J., W. R. Harlan, and P. E. Leaverton. Blood pressure in adolescence. The U.S. Health Examination Survey. Hypertension 1: 566 - 573, 1979.PubMedCrossRefGoogle Scholar
  12. 12.
    Culpepper, W. S. Cardiac anatomy and function in juvenile hypertension. Am. J. Med. Sept.: 57 - 59, 1983.Google Scholar
  13. 13.
    Culpepper, W. S., P. C. Sodt, F. H. Messerli, D. C. Ruschhaupt, and R. A. Arcilla. Cardiac status in juvenile borderline hypertension. Ann. Intern. Med. 98: 1, 1983.PubMedCrossRefGoogle Scholar
  14. 14.
    Daughaday, W. H., L. S. Phillips, and M. L. Mueller. The effects of insulin and growth hormone on the release of somatomedin by the isolated rat liver. Endocrinology 98: 1214 - 1219, 1976.PubMedCrossRefGoogle Scholar
  15. 15.
    DeFronzo, R. A. The effect of insulin on renal sodium metabolism. Diabetologia 21: 165171, 1981.Google Scholar
  16. 16.
    DeFronzo, R. A., M. Goldberg, and Z. S. Agus. The effects of glucose and insulin on renal electrolyte transport. J. Clin. Invest. 58: 83 - 90, 1976.CrossRefGoogle Scholar
  17. 17.
    DeLuise, M., G. L. Blackburn, and J. S. Flier. Reduced activity of the red cell sodium-potassium pump in human obesity. N. Engl. J. Med. 303: 1017 - 1022, 1980.CrossRefGoogle Scholar
  18. 18.
    DeSweit, M., P. M. Fayers, and E. A. Shineburne. Blood pressure in four and five year old children. The effects of environmental and other factors in its measurement—the Brompton Study. Hypertension 2: 501 - 505, 1984.CrossRefGoogle Scholar
  19. 19.
    Diebert, D. C., and R. A. DeFronzo. Epinephrine-induced insulin resistance in man. J. Clin. Invest. 65: 717 - 721, 1980.CrossRefGoogle Scholar
  20. 20.
    Dimsdale, J. E., R. Grahm, M. G. Ziegler, R. Zusman, and C. C. Berry. Age, race, diagnosis, and sodium effects on the pressor response to infused norepinephrine. Hypertension 10: 564 - 569, 1987.PubMedCrossRefGoogle Scholar
  21. 21.
    Eigenmann, J. E., J. Patterson, J. Zapf, and E. R. Froesch. Insulin-like growth factor I in the dog: a study of different dog breeds and in dogs with growth hormone elevation. Acta Endocrinol. (Copenh.) 105: 294 - 301, 1984.Google Scholar
  22. 22.
    Falkner, B., and H. Kushner. Race differences in stress induced reactivity in young adults. Health Psychol. 8(5): 613 - 627, 1989.Google Scholar
  23. 23.
    Falkner, B., and H. Kushner. The effect of chronic sodium loading on the cardiovascular response to stress in young blacks and whites. Hypertension 15: 36 - 43, 1990.PubMedCrossRefGoogle Scholar
  24. 24.
    Falkner, B., G. Onesti, E. T. Angelakos, M. Fernandez, and C. Langman. Cardiovascular response to mental stress in normal adolescence with hypertensive parents. Hypertension 1: 23 - 29, 1979.PubMedCrossRefGoogle Scholar
  25. 25.
    Falkner, B., H. Kushner, G. Onesti, and E. T. Angelakos. Cardiovascular characteristics in adolescents who develop essential hypertension. Hypertension 3: 251 - 256, 1981.CrossRefGoogle Scholar
  26. 26.
    Falkner, B., D. T. Lowenthal, M. B. Affrime, and B. Hamstra. R wave amplitude during aerobic exercise in hypertensive adolescents following treatment. Am. J. Cardiol. 51: 459 - 463, 1983.PubMedCrossRefGoogle Scholar
  27. 27.
    Falkner, B., D. T. Lowenthal, M. B. Affrime, and B. Hamstra. R wave amplitude changes in hypertensive children. Am. J: Cardiol. 50: 152 - 156, 1982.CrossRefGoogle Scholar
  28. 28.
    Ferrannini, E., G. Buzzigoli, R. Bonadonna, M. A. Giorico, M. Oleggini, L. Graziadei, R. Pedrinelli, L. Brandi, and S. Bevilacqua. Insulin resistance in essential hypertension. N. Engl. J. Med. 317: 350 - 357, 1987.PubMedCrossRefGoogle Scholar
  29. 29.
    Florey, C. V., S. Uppal, and S. Lowy. Relation between blood pressure, weight, and plasma sugar and serum insulin levels in school children aged 9-12 years in Westland Holland. Br. Med. J. 1: 1368 - 1371, 1976.PubMedCrossRefGoogle Scholar
  30. 30.
    Folkow, B. Physiological aspects of primary hypertension. Physiol. Rev. 62: 347 - 504, 1982.PubMedGoogle Scholar
  31. 31.
    Fournier, A. M., M. T. Gadia, D. B. Kubrusly, J. S. Skyler, and J. M. Sosenko. Blood pressure, insulin, and glycemia in non diabetic subjects. Am. J. Med. 80: 861 - 864, 1986.PubMedCrossRefGoogle Scholar
  32. 32.
    Fredrickson, M. Racial differences in cardiovascular reactivity to mental stress in essential hypertension. J. Hypertens. 4: 325 - 331, 1986.CrossRefGoogle Scholar
  33. 33.
    Froesch, E. R., and J. Zapf. Insulin-like growth factors and insulin• comparative aspects. Diabetologia 28: 485 - 493, 1985.PubMedCrossRefGoogle Scholar
  34. 34.
    Garay, R. P., C. Nazaret, P. Hannaert, and M. Price. Abnormal Na, K cotransport function in a group of patients with essential hypertension. Eur. J. Clin. Invest. 13: 311 - 320, 1983.PubMedCrossRefGoogle Scholar
  35. 35.
    Gillum, R. F. Pathophysiology of hypertension in blacks and whites. Hypertension 1: 468475, 1979.Google Scholar
  36. 36.
    Goldring, D., A. Hernandez, S. Choi, J. Y. Lee, S. Londe, F. T. Lindgren, and R. M. Barton. Blood pressure in a high school population. II. Clin. J. Pediatr. 95: 298 - 303, 1979.CrossRefGoogle Scholar
  37. 37.
    Goldstein, D. S. Plasma catecholamines and essential hypertension: an analytical review. Hypertension 5: 86 - 90, 1983.PubMedCrossRefGoogle Scholar
  38. 38.
    Goldstein, D. S., C. R. Lake, B. Chernow, M. G. Ziegler, M. D. Coleman, A. A. Taylor, J. R. Mitchell, I. J. Kopin, and H. R. Keiser. Age dependence of hypertensive-normotensive differences in plasma norepinephrine. Hypertension 5: 100-104, 1983.Google Scholar
  39. 39.
    Hallbach, M. Interaction of central autonomic hypersensitivity and environmental stimuli: importance for development of spontaneously hypertensive rats. In: Regulation of Blood Pressure by the Central Nervous System, edited by G. Onesti, M. Fernandez, and K. Kim. Grune & Stratton, New York, 1976, p. 129.Google Scholar
  40. 40.
    Harlan, W. R., J. Cornoni-Huntley, and P. E. Leaverton. Blood pressure in childhood. The National Health Examination Survey. Hypertension 1: 599 - 604, 1979.CrossRefGoogle Scholar
  41. 41.
    Heymsfield, S. B., C. McManus, V. Stevens, and J. Smith. Muscle mass as a reliable indication of protein-energy malnutrition severity and outcome. Am. J. Clin. Nutr. 35: 1192 - 1199, 1982.PubMedGoogle Scholar
  42. 42.
    Hilton, P. J. Cellular sodium transport in essential hypertension. N. Engl. J. Med. 314: 222 - 229, 1986.PubMedCrossRefGoogle Scholar
  43. 43.
    Julius, S. Borderline hypertension: an overview. Med. Clin. North Am. 61: 595 - 605, 1977.Google Scholar
  44. 44.
    Kaiser, N., A. Tur-Sinai, M. Hasin, and E. Cerasi. Binding, degradation and biological activity of insulin in vascular smooth muscle cells. Am. J. Physiol. 249 (Endocrinol. Metab. 12): E292 — E298, 1985.PubMedGoogle Scholar
  45. 45.
    Katz, S. H., M. C. Hediger, J. I. Schall, E. J. Bowers, W. F. Barker, S. Aurand, P. B. Ebelith, A. B. Gruskin, and J. S. Parks. Blood pressure, growth and maturation from childhood to adolescence. Hypertension 2(Suppl): I-55-61, 1980.Google Scholar
  46. 46.
    Katz, S. L., M. L. Hediger, B. S. Zemel, and J. S. Parks. Blood pressure, body fat, and dehydroepiandrosterone sulfate variation in adolescence. Hypertension 8: 277 - 284, 1986.PubMedCrossRefGoogle Scholar
  47. 47.
    King, G. L., D. Goodman, S. Buzney, A. Moses, and C. R. Kahn. Receptors and growth-promoting effects of insulin and insulin-like growth factors on cells from bovine retinal capillaries and aorta. J. Clin. Invest. 75: 1028 - 1036, 1985.PubMedCrossRefGoogle Scholar
  48. 48.
    Kushner, H., and B. Falkner. A harmonic analysis of cardiac response of normotensive and hypertensive adolescents during stress. J. Hum. Stress 7: 21 - 27, 1981.CrossRefGoogle Scholar
  49. 49.
    Laird, W. P., and D. E. Fixler. Left ventricular hypertrophy in adolescents with elevated blood pressure: assessment by chest roentgenography, electrocardiography, and echocardiography. Pediatrics 67: 255 - 259, 1981.PubMedGoogle Scholar
  50. 50.
    Lauer, R. M., and W. R. Clark. A longitudinal view of blood pressure during childhood: the Muscatine Study. Stat. Med. 7: 47 - 57, 1988.PubMedCrossRefGoogle Scholar
  51. 51.
    Lauer, R. M., A. R. Anderson, R. Beaglehole, and T. L. Burns. Factors related to tracking of blood pressure in children. U.S. National Center for Health Statistics Health Examination Surveys Cycles II and III. Hypertension 6: 307 - 314, 1984.CrossRefGoogle Scholar
  52. 52.
    Lauer, R. M., W. R. Clarke, and R. Beaglehole. Level, trend and variability of blood pressure during childhood: the Muscatine Study. Circulation 69: 242 - 249, 1984.PubMedCrossRefGoogle Scholar
  53. 53.
    Lawler, K. A., and M. T. Allen. Risk factors for hypertension in children: their relationship to psychophysiologic responses. J. Psychosom. Res. 23: 199 - 204, 1981.CrossRefGoogle Scholar
  54. 54.
    Light, K. C., and P. A. Obrist. Cardiovascular reactivity to behavioral stress in young males with and without marginally elevated causal systolic pressures: comparison of clinic, home, and laboratory measures. Hypertension 2: 802 - 809, 1980.PubMedCrossRefGoogle Scholar
  55. 55.
    Light, K. C., and P. A. Obrist. Cardiovascular reactivity to behavioral stress in young males with and without marginally elevated casual systolic pressure: a comparison of clinic, home, and laboratory measures. Psychophysiology 19: 481 - 489, 1982.CrossRefGoogle Scholar
  56. 56.
    Light, K. C., P. A. Obrist, A. Sherwood, S. A. James, and D. S. Strogatz. Effects of race and marginally elevated blood pressure on responses to stress. Hypertension 10: 555 - 563, 1987.PubMedCrossRefGoogle Scholar
  57. 57.
    Londe, S., J. J. Bourgoignie, A. M. Robson, and D. Goldring. Hypertension in apparently normal children. J. Pediatr. 78: 569 - 573, 1971.PubMedCrossRefGoogle Scholar
  58. 58.
    Luft, F. C., C. E. Grim, J. T. Higgins, Jr., and M. H. Weinberger. Differences in response to sodium administration in normotensive white and black subjects. J. Lab. Clin. Med. 90: 555 - 562, 1977.PubMedGoogle Scholar
  59. 59.
    Mahoney, L. T., W. R. Clarke, A. L. Mark, and R. M. Lauer. Forearm vascular resistance in. the upper and lower quartiles of blood pressure in adolescent boys. Pediatr. Res. 16: 163 - 166, 1982.PubMedCrossRefGoogle Scholar
  60. 60.
    Manicardi, V., L. Camellini, G. Bellodi, C. Caselli, and E. Ferrannini Evidence for an association of high blood pressure and hyperinsulinemia in obese man. J. Clin. Endocrinol. Metab. 62: 1302 - 1304, 1986.PubMedCrossRefGoogle Scholar
  61. 61.
    Manuck, S. B., and J. M. Proietti. Parental hypertension and cardiovascular response to cognitive and isometric challenge. Psychophysiology 19: 481 - 489, 1982.PubMedCrossRefGoogle Scholar
  62. 62.
    Masuo, K., T. Ogihara, Y. Kumahara, A. Yamatodani, and H. Wada. Increased plasma nor-epinephrine in young patients with essential hypertension under three sodium intakes. Hypertension 6: 315 - 321, 1984.PubMedCrossRefGoogle Scholar
  63. 63.
    Merimee, T. J., J. Zapf, and E. R. Froesch. Insulin-like growth factors (IGFs) in pygmies and subjects with the pygmy trait: characterization of the metabolic actions of IGF-I and IGF-II in man. J. Clin. Endocrinol. Metab. 55: 1081 - 1087, 1982.CrossRefGoogle Scholar
  64. 64.
    Merimee, T. J., J. Zapf, B. Hewlett, and L. L. Cavalli-Forza. Insulin-like growth factors in pygmies. N. Engl. J. Med. 316: 906 - 911, 1987.PubMedCrossRefGoogle Scholar
  65. 65.
    Modan, M., H. Halkin, S. Almog, A. Lusky, A. Eshkol, M. Shefi, A. Shitrit, and Z. Fuehs. Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance. J. Clin. Invest. 75: 809 - 817, 1985.PubMedCrossRefGoogle Scholar
  66. 66.
    Moore, R. D. Effects of insulin ion transport. Biochim. Biophys. Acta 737: 1 - 49, 1983.PubMedCrossRefGoogle Scholar
  67. 67.
    Mott, D. M., R. L. Clark, W. J. Andrews, and J. E. Foley. Insulin resistant Na pump activity in adipocytes from obese humans. Am. J. Physiol. 249 (Endocrinol. Metab. 12): E160164, 1985.Google Scholar
  68. 68.
    Munger, R. G., R. J. Prineas, and O. Gomez-Marin. Persistent elevation of blood pressure among children with a family history of hypertension: the Minneapolis Childrens Blood Pressure Study. J. Hypertens. 6: 647 - 653, 1988.PubMedCrossRefGoogle Scholar
  69. 69.
    Murphy, J. K., B. S. Alpert, D. M. Moes, and G. W. Somes. Race and cardiovascular reactivity, a neglected relationship. Hypertension 8: 1075 - 1083, 1986.PubMedCrossRefGoogle Scholar
  70. 70.
    National Health Survey, Blood pressure of adults by race and area in the United States, 1960-1962, National Center for Health Statistics Series II, No. 5, Washington, D.C., U.S. Department of Health, Education and Welfare, 1964.Google Scholar
  71. 71.
    National Health Survey, Blood pressure of persons 18-74 years in the United States, 19711972, National Center for Health Statistics Series II, No. 150, Washington, D.C., U.S. Department of Health, Education and Welfare, 1975.Google Scholar
  72. 72.
    Nestle, P. J. Blood pressure and catecholamine excretion after mental stress in labile hypertension. Lancet 1: 692 - 698, 1969.CrossRefGoogle Scholar
  73. 73.
    Prineas, R. J., R. S. Gillum, H. Horibe, and P. F. Hannan. Minneapolis Childrens Blood Pressure Study. Part II. Multiple determinants of blood pressure. Hypertension 2(Suppl): 1-24-31,1980.Google Scholar
  74. 74.
    Reaven, G. M., and B. B. Hoffman. A role for insulin in the aetiology and course of hypertension. Lancet 2: 435 - 436, 1987.PubMedCrossRefGoogle Scholar
  75. 75.
    Report of the Task Force on Blood Pressure Control in Children. Pediatrics 58(Suppl): 797810, 1977.Google Scholar
  76. 76.
    Rocchini, A. P., Katch, A. Schork, and R. P. Kelch. Insulin and blood pressure during weight loss in obese adolescents. Hypertension 10: 267 - 273, 1987.PubMedCrossRefGoogle Scholar
  77. 77.
    Rosenbaum, P. A., R. C. Elston, S. R. Srinivasan, L. S. Weber, and G. S. Berenson. Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Predictive value of parental measures in determining cardiovascular risk factor variables in early life. Pediatrics 80: 807 - 816, 1987.PubMedGoogle Scholar
  78. 78.
    Rowe, J. W., J. B. Young, K. L. Minaker, A. L. Stevens, J. Pallotta, and L. Landsberg. Diabetes 30: 219 - 225, 1981.PubMedGoogle Scholar
  79. 79.
    Safar, M. E., Y. A. Weiss, J. A. Levenson, G. M. London, and P. L. Milliez. Hemodynamic study of 85 patients with borderline hypertension. Am. J. Cardiol. 31: 315 - 322, 1973.CrossRefGoogle Scholar
  80. 80.
    Schieken, R. M., W. R. Clarke, and R. M. Lauer. Left ventricular hypertrophy in children with blood pressure in the upper quartiles of distribution. The Muscatine Study. Hypertension 3: 669 - 675, 1981.Google Scholar
  81. 81.
    Schieken, R. M., W. R. Clarke, and R. M. Lauer. The cardiovascular response to exercise in children across the blood pressure distribution. The Muscatine Study. Hypertension 5: 71 - 79, 1983.PubMedCrossRefGoogle Scholar
  82. 82.
    Shear, C. L., G. L. Burke, D. S. Freedman, and G. S. Berenson. Value of childhood blood pressure measurements and family history in predicting future blood pressure status: results from 8 years of follow-up in the Bogalusa Heart Study. Pediatrics 77: 862 - 869, 1986.PubMedGoogle Scholar
  83. 83.
    Sloan, I., P. Saul, and I. Bihler. Influence of adrenalin or sugar transport in soleus, a red skeletal muscle. Mol. Cell. Endocrinol. 10: 3 - 12, 1978.PubMedCrossRefGoogle Scholar
  84. 84.
    Smoak, C. G., G. L. Burke, L. S. Webber, D. W. Harsha, S. R. Srinivasan, and G. S. Berenson. Relation of obesity to clustering of cardiovascular disease risk factors in children and young adults. Am. J. Epidemiol. 125: 364 - 372, 1987.PubMedGoogle Scholar
  85. 85.
    Soto, L. F., D. A. Kitcuchi, R. A. Arcilla, D. D. Savage, and G. S. Berenson. Echocardiographic functions and blood pressure levels in children and young adults from a biracial population. The Bogalusa Heart Study. Am. J. Med. Sci. 297: 271 - 279, 1989.CrossRefGoogle Scholar
  86. 86.
    Task Force on Blood Pressure Control in Children. Report of the Second Task Force on Blood Pressure Control in Children, 1987. Pediatrics 79: 1 - 25, 1987.Google Scholar
  87. 87.
    Vital Statistics of the United States, 1973, Vol. II. Mortality Pathology U.S. Department of Health, Education and Welfare. Public Health Service, National Center for Health Statistics, 1977.Google Scholar
  88. 88.
    Voors, A. W., T. A. Foster, R. R. Frerichs, L. S. Weber, and G. S. Berenson. Studies of blood pressure in children ages 5-14 years in a total bi-racial community. Circulation 54: 319 - 347, 1976.PubMedCrossRefGoogle Scholar
  89. 89.
    Voors, A. W., L. S. Webber, D. H. Harsha, and G. S. Berenson. Racial differences in cardiovascular risk factors of youth. Bogalusa Heart Study. Abstracts of 18th Annual Conference on Cardiovascular Disease, Epidemiology. Dallas, Am. Heart Assoc., 1978.Google Scholar
  90. 90.
    Voors, A. W., B. Radhakrishnamurthy, S. R. Srinivasan, L. S. Webber, and G. S. Berenson. Plasma glucose level related to blood pressure in 272 children ages 7-15 years sampled from a total biracial population. Am. J. Epidemiol. 113: 347 - 356, 1981.PubMedGoogle Scholar
  91. 91.
    Voors, A. W., L. S. Webber, and G. S. Berenson. Time cost study of blood pressure in children over a three year period. Hypertension 2(Suppl): I-102-108, 1980.Google Scholar
  92. 92.
    Walass, O., and E. Walass. Effects of epinephrine on rat diaphragm. J. Biol. Chem. 187: 769 - 776, 1950.Google Scholar
  93. 93.
    Weinberger, M. H., J. Z. Miller, F. C. Luft, C. E. Grim, and N. S. Fineberg. Definitions and characteristics of sodium sensitivity and blood pressure resistance. Hypertension 8(Suppl II): II-127—II-134, 1986.Google Scholar
  94. 94.
    Wilson, S. L., A. Gaffney, W. P. Laird, and D. E. Fixler. Body size, composition, and fitness in adolescents with elevated blood pressure. Hypertension 7: 417 - 422, 1985.PubMedGoogle Scholar
  95. 95.
    Wormsley, J., and J. V. Durnin. A comparison of the skinfold method with extent of overweight and various height-weight relationships in assessment of obesity. Br. J. Nutr. 38: 271 - 284, 1977.CrossRefGoogle Scholar
  96. 96.
    Zinner, S. A., P. S. Levy, and E. H. Kass. Family aggregation of blood pressure in childhood. N. Engl. J. Med. 283: 461, 1971.Google Scholar

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  • Bonita Falkner

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