Abstract
The focus of this chapter is on the role of the carotid and aortic bodies in controlling the pulmonary vasculature during hypoxia. It should be stated at the outset that control of the pulmonary vasculature is an extremely controversial area. On first survey it would appear that data presented by one distinguished investigator simply contradicts the data presented by a second equally distinguished investigator. Closer inspection of the fairly abundant literature in this area reveals that responses of the pulmonary vasculature to almost any challenge can vary, sometimes radically, among species, can be a function of the preexisting tone in the vessel, can be influenced by anesthesia, and can be difficult even to measure. Hence, making generalizations about the pulmonary vasculature can be a rather risky business.
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Fitzgerald, R.S., Dehghani, G.A., Sham, J.S.K., Shirahata, M. (1991). Pulmonary Hypoxic Vasoconstrictor Response: Modulation by the Peripheral Arterial Chemoreceptors. In: Lahiri, S., Cherniack, N.S., Fitzgerald, R.S. (eds) Response and Adaptation to Hypoxia. Clinical Physiology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7574-3_19
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DOI: https://doi.org/10.1007/978-1-4614-7574-3_19
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