The Respiratory System

  • Jerome A. Dempsey
  • Brian J. Whipp


The history of science deals with events and concepts—but above all, with people. In our treatment of the history of respiratory physiology as applied to exercise, we have chosen to follow the lead of J.B. West and his contributors (155) in emphasizing the people and ideas theme used in their recent history of respiratory physiology. To this end, we have corresponded with several of the major scientists in this area over the past 50 years who have shared their personal motivation to study respiration and exercise, their own perception of their contributions, and finally the important questions they feel remain unanswered in the field. We have also chosen to subdivide our topic into studies of (1) the mechanical aspects of the lung and chest wall, (2) alveolar to arterial gas exchange, (3) the control of exercise hyperpnea, and (4) the adaptability of the pulmonary system and its role in the limitation of maximal O2 transport and exercise performance.


Clay Nickele Depression Acidity Histamine 


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© American Physiological Society 2003

Authors and Affiliations

  • Jerome A. Dempsey
  • Brian J. Whipp

There are no affiliations available

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