Abstract
In 1935 Niels Bohr and Georg von Hevesy invited Krogh to collaborate in biological experiments with “heavy” water, i.e. water in which some of the hydrogen ions are replaced with the isotope deuterium (D) bearing twice the atomic weight of hydrogen.1
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It is my task today to present some thoughts about a new and, as I believe, extremely powerful tool in biological and biochemical research: A small number of isotopes which can be readily distinguished and quantitatively determined by relatively simple physical means.
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References
August Krogh’s will, handwritten among his papers.
AK to Hagedorn, Aug. 1938.
Hagedorn to AK, Aug. 8, 1938.
AK to MK, Sept. 1938.
Told to Ellen Krogh by Professor Jacob Poulsen.
MK to Ellen, Aug. 24, 1940.
John Keegan: The Second World War. Viking Penguin Group, New York, 1989.
Told by P. F. Scholander. As expected by Krogh, Scholander became one of the world’s foremost comparative physiologists. He stayed in America, having obtained his American citizenship after he had joined the U.S. Army.
Correspondence between MK and Ellen, 1940–43.
Correspondence between MK and Agnes, 1940–43.
AK to Ellen, March 3, 1943.
AK to Ellen, March 17, 1943.
Correspondence between AK and E. Hohwü Christensen.
AK to Ellen, May 9, 1943.
AK to Ellen, April 19, 1943. The paper he planned to write became the Croonian Lecture to the Royal Society in 1945. AK Publ. #285.
Harold Flender: Rescue in Denmark. Simon and Schuster, New York, 1963.
AK to Ellen, Dec. 26, 1943.
Niels Blædel: Harmonie og enhed, Niels Bohr en Biografi (Harmony and unity, Niels Bohr a biography). Carlsberg Fondet and Rhodos, Copenhagen, 1985.
AK to Ellen, July 11, 1944.
John Toland: The last days. Random House, New York, 1965.
Told by Karen Krogh.
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© 1995 American Physiological Society
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Schmidt-Nielsen, B. (1995). The Introduction of Isotopes (1935–1944). In: August and Marie Krogh. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7530-9_18
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DOI: https://doi.org/10.1007/978-1-4614-7530-9_18
Publisher Name: Springer, New York, NY
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