The Happiest Years (1923–1938)

  • Bodil Schmidt-Nielsen


Returning from America, August turned his attention not only to insulin production and capillary physiology but also to getting a larger, better equipped laboratory. On January 10, 1923, he wrote a letter to Dr. Rufus Cole at the Hospital of the Rockefeller Institute for Medical Research in New York: “I take the liberty to approach you with a proposition which you will perhaps consider extremely preposterous. I am inclined to look upon it in that way myself but on the other hand it might be possible to take it seriously and I venture to believe that it would, if carried out, be of such value in furthering the study of experimental medicine that I feel justified in asking your opinion.” He explained that the rooms in his present laboratory were few, small, and poorly lighted with no room for a library or even for a secretary, as they had to use every inch of space for experimental work. He regretted that there was never enough room for the American graduate students who wished to work with him. With improved laboratory facilities, he felt, it would be possible to increase, probably by 100 percent, “the amount of research work done in my laboratory without in any way lowering its standards.... I am now 48 years old. I am perfectly sound and expect to have about 20 years of useful experimental work before me. I believe that there is a fair chance that I shall repay in scientific work and in training of workers the outlay which it would require to put me in a position in which my capabilities for work could be utilized to the full.”1


Canary Island Living Room Dung Beetle Rockefeller Foundation Summer Vacation 
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Notes and References

  1. 1.
    Eugene M. Landis: Professor August Krogh: An appreciation. In Capillary Permeability, the transfer of molecules and ions between capillary blood and tissue. Alfred Benzon Symposium II, 1969. Munksgärd, Copenhagen, 1970.Google Scholar
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    E. Landis: Preface to the reprinted edition of A. Krogh’s The Anatomy and Physiology of Capillaries. Hafner, New York, 1959.Google Scholar
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    P. Brandt Rehberg: August Krogh, November 15, 1874-September 13, 1949. (Yale J. Biol. Med., 24, 1951 ).Google Scholar
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    AK Publ. #121.Google Scholar
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    Richard Ege later became professor of biochemistry and had his laboratory at the Rockefeller Institute in Copenhagen.Google Scholar
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    Th. B. Wernoe’s doctoral dissertation from the Zoophysiological Laboratory was published as Viscero-Cutane Reflexe. Springer Verlag, 1925; and Über den Verlauf und die Verteilung präganlionärer sympatischen Bahnen bei Fischen, in Physiological papers dedicated to Prof. A. Krogh, 1926.Google Scholar
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    C. K. Drinker & E. D. Churchill: A graphite suspension for intravital injection of capillaries. (Proc. Royal Soc. B., 101, 1927). C. K. Drinker, The permeability and diameter of the capillaries in the web of the brown frog (R. temporia) when perfused with solutions containing pituitary extract and horse serum. (J. Physiol., 63, 1927 ).Google Scholar
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    AK Publ. #155.Google Scholar
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    AK Publ. #149; Leonard Share: Vasopressin and regulation of water homeostasis. In Endocrinology. People and ideas. Ed. S. M. McCann. American Physiological Society, Bethesda, Maryland, 1988. Pages 1–21.Google Scholar
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    Bj. Vimtrup: Beiträge zur Anatomie der Capillaren. I Über contractile elementen in der gefässwand der Blutcapillaren. (Zeitschr. f. Anat. u. Entwicklungsgeschichte, 65, 1922); Beiträge zur Anatomie der Capillaren. II Weitere Untersuchungen über contractile elementen in der gefässwand der Blutcapillaren. (Zeitschr. f. Anat. u. Entwicklungsgeschichte, 68, 1923 ).Google Scholar
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    David E. Sims: The pericyte—a review. (Tissue and Cell, 18, 153–174, 1986); Recent advances in pericyte biology—Implications for health and disease. (Can. J. Cardiol., 7, 431–443, 1991.Google Scholar
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    Rehberg’s tape-recorded memoirs, 1975, in the Royal Library of Denmark.Google Scholar
  13. 13.
    Bensley to AK. Dec. 22, 1927.Google Scholar
  14. 14.
    Christian Crone: Trwk af Kapillwrfysiologiens Udvikling. Festschrift udgivet of Kobenhavns Universitet i anledning af Universitetets Arsfest 1974. Bianco Lunos Bogtrykkeri AIS, Copenhagen, 1974.Google Scholar
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    Madeleine Field: The reactions of blood capillaries in the frog and rat to mechanical and electrical stimulation. (Skand. Arch. f. Physiol., 72, 1935 ).Google Scholar
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    B. W. Zweifach: A micromanipulative study of blood capillaries. (Anat. Rec., 59, 83–108, 1934 ).CrossRefGoogle Scholar
  17. 17.
    Henry K. Beecher: The active control of all parts of the capillary wall by the sympathetic nervous system. (Skand. Archiv. f. Physiol., 73, 1936 ).Google Scholar
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    Beecher to AK, June 26, 1937.Google Scholar
  19. 19.
    Robert Chambers & B. W. Zweifach: Topography and function of the mesenteric capillary circulation. (Am. J. Anat., 75, 173–205, 1947 ).Google Scholar
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    J. A. G. Rhodin, personal communication; J. A. G. Rhodin & H. Fujita: Capillary growth in the mesentery of normal young rats. Intravital and electron microscope analysis. (J. Submicrosc. Pathology, 21, 1–34, 1989 ).Google Scholar
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    J. Stingl: Zur Ultrastruktur des terminalen Gefässbettes der Skeletmuskulatur. (Acta Anat., 80, 255–272, 1971 ).PubMedCrossRefGoogle Scholar
  22. 22.
    P. B. Rehberg: Studies on kidney function. I. The rate of filtration and reabsorption in the human kidney; Studies on kidney function. II. The excretion of urea and chlorine analyzed according to a modified filtration reabsorption theory. (The Biochem. fount., 20, 447–482, 1926 ).Google Scholar
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    A. N. Richards & J. B. Barnwell: Experiments concerning the question of secretion of phenolsulphonephthalein by the renal tubules. (Proc. Royal Soc. B., 102, 1927 ).Google Scholar
  24. 24.
    E. M. Landis: Capillary pressure and hyperemia in muscle and skin of the frog. (Am. J. Physiol., 98, 1931); Abby H. Turner: The validity of determination of colloid osmotic pressure of serum. (J. Biol. Chem., 96, 1932); A. Krogh, A. H. Turner & E. M. Landis: A celluloid capsule for measuring venous pressure. (J. Clin. Invest., 11, 1932); A. Krogh, E. M. Landis & A. H. Turner: The movement of fluid through the human capillary wall in relation to venous pressure and to the colloid osmotic pressure of the blood. (J. Clin. Invest., 11, 1933 ).Google Scholar
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    Capillary Permeability, the transfer of molecules and ions between capillary blood and tissue. Alfred Benzon Symposium II, 1969. Munksg.rd, Copenhagen, 1970.Google Scholar

Copyright information

© American Physiological Society 1995

Authors and Affiliations

  • Bodil Schmidt-Nielsen
    • 1
  1. 1.Department of PhysiologyUniversity of FloridaGainesvilleUSA

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