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Flow-Induced Vasodilation of Large Arteries: From “Ascending Reflex” to EDRF

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Flow-Dependent Regulation of Vascular Function

Part of the book series: Clinical Physiology Series ((CLINPHY))

Abstract

The physical forces acting on the wall of blood vessels are shear stress and pressure. Shear stress acts in the same direction as flow, while pressure is exerted at right angles to the axis of flow. Both have an influence on vascular tone and also contribute to long-term structural and functional adaptation of the blood vessels.

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Authors
  1. Gabor M. Rubanyi
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Editors and Affiliations

  1. Department of Pharmacology, College of Medicine, University of Vermont, Burlington, Vermont, USA

    John A. Bevan M.D.

  2. Department of Physiology, New York Medical College, Valhalla, New York, USA

    Gabor Kaley Ph.D.

  3. Berlex Biosciences, Richmond, California, USA

    Gabor M. Rubanyi M.D., Ph.D.

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© 1995 American Physiological Society

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Rubanyi, G.M. (1995). Flow-Induced Vasodilation of Large Arteries: From “Ascending Reflex” to EDRF. In: Bevan, J.A., Kaley, G., Rubanyi, G.M. (eds) Flow-Dependent Regulation of Vascular Function. Clinical Physiology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7527-9_6

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  • DOI: https://doi.org/10.1007/978-1-4614-7527-9_6

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7527-9

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