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Cell Culture Model for the Study of Vascular Complications of Diabetes: The Effect of High Glucose Levels on Metabolism and Growth of Vascular Cells

  • Chapter
Hyperglycemia, Diabetes, and Vascular Disease

Part of the book series: Clinical Physiology Series ((CLINPHY))

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Abstract

Vascular complications affect all diabetic patients to some extent and involve both microvessels and macrovessels. In this chapter we discuss studies that show the effects of elevated glucose levels on the metabolism of retinal and aortic vascular cells in culture.

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Authors
  1. George L. King
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  2. Teruo Shiba
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  3. Edward P. Feener
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  4. Ramesh Nayak
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Editor information

Editors and Affiliations

  1. Diabetes and Metabolism Unit, Evans Memorial Department of Clinical Research and Department of Physiology, Boston University School of Medicine, Boston, Massachusetts, USA

    Neil Ruderman

  2. Department of Pathology, Washington University School of Medicine, St. Louis, Missouri, USA

    Joseph Williamson

  3. Diabetes Research Center and Departments of Medicine and Pathology, Albert Einstein College of Medicine, Bronx, New York, USA

    Michael Brownlee

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© 1992 American Physiological Society

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King, G.L., Shiba, T., Feener, E.P., Nayak, R. (1992). Cell Culture Model for the Study of Vascular Complications of Diabetes: The Effect of High Glucose Levels on Metabolism and Growth of Vascular Cells. In: Ruderman, N., Williamson, J., Brownlee, M. (eds) Hyperglycemia, Diabetes, and Vascular Disease. Clinical Physiology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7524-8_9

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  • DOI: https://doi.org/10.1007/978-1-4614-7524-8_9

  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7524-8

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