Airway and Pulmonary Afferents and Reflexes: A Historical Survey

  • John Widdicombe
  • Giuseppe Sant’Ambrogio
Part of the People and Ideas book series (PEOPL)


Breathing is thought to be critically dependent for its optimal performance on a variety of sensory feedbacks from multiple sources. This sensory information adjusts the functions of the respiratory controller to the continuously changing demands for gas exchange and other non-metabolic behavioral activities. The purpose of this chapter is to examine the historical development of our knowledge about the reflex control of breathing and related sensory information.


Nasal Cavity Recurrent Laryngeal Nerve Nasal Mucosa Airway Smooth Muscle Tracheobronchial Tree 
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© American Physiological Society 1996

Authors and Affiliations

  • John Widdicombe
  • Giuseppe Sant’Ambrogio

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