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The History of Chemoreception

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Respiratory Physiology

Part of the book series: People and Ideas ((PEOPL))

Abstract

From our current perspective the purpose of respiration is well understood. The necessity of having mechanisms sensitive to levels of oxygen (O2) or carbon dioxide (CO2) that determine respiratory behavior seems entirely clear. However, the existence of these two chemicals was unknown to the pioneer observers of breathing. For them, respiration addressed other needs. Almost two millenia passed before biologists and physicians understood that breathing is a process needed to acquire O2 and eliminate CO2. When O2 and CO2 were recognized as chemicals intimately involved with life, and respiration was appreciated as the process of transfer, investigators could focus more precisely on the chemosensitive loci and the processes of chemoreception. The discovery of O2 and CO2 are interesting chapters in the history of chemoreception, filled with many talented, imaginative investigators from the ancients to the prime contributors of the 17th and 18th centuries. But these stories are told elsewhere in this volume. This chapter will begin with investigators who knew that the real purpose of respiration is to acquire O2 and to discharge CO2.

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Authors
  1. Robert S. Fitzgerald
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  2. Sukhamay Lahiri
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Editors and Affiliations

  1. Department of Medicine, University of California, San Diego, La Jolla, California, USA

    John B. West

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© 1996 American Physiological Society

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Fitzgerald, R.S., Lahiri, S. (1996). The History of Chemoreception. In: West, J.B. (eds) Respiratory Physiology. People and Ideas. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7520-0_10

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  • DOI: https://doi.org/10.1007/978-1-4614-7520-0_10

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