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Sodium-Potassium Pump

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Book cover Membrane Transport

Part of the book series: People and Ideas ((PEOPL))

Abstract

The idea of a pump in the cell membrane was introduced by R. B. Dean in 1941 in a paper entitled “Theories of Electrolyte Equilibrium in Muscle” (20). Referring to experiments by L. A. Heppel in 1938, by Heppel and C. L. A. Schmidt in 1939, and by H. B. Steinbach in 1940 (see ref. 20), Dean concluded: “the muscle can actively move potassium and sodium against concentration gradients... this requires work. Therefore there must be some sort of a pump possibly located in the fiber membrane, which can pump out the sodium or, what is equivalent, pump in the potassium.”

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  1. Jens C. Skou
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  1. Harvard Medical School, Boston, Massachusetts, USA

    Daniel C. Tosteson (Dean) (Dean)

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© 1989 American Physiological Society

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Skou, J.C. (1989). Sodium-Potassium Pump. In: Tosteson, D.C. (eds) Membrane Transport. People and Ideas. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7516-3_5

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