The Patient Who Could Not Raise Her Head

Vecuronium, gentamicin
  • Nicole L. Varela
  • Toby N. Weingarten
  • Juraj Sprung


This case discusses a synergistic pharmacodynamic interaction between vecuronium and gentamicin.


Pharmacodynamics Synergistic Synergism Neuromuscular weakness Neuromuscular blocker Vecuronium Gentamicin Aminoglycoside Antibiotic Atracurium Presynaptic calcium ion–sensing receptors Acetycholine Neuromuscular junction Presynaptic Motor end plate 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Nicole L. Varela
    • 1
  • Toby N. Weingarten
    • 2
  • Juraj Sprung
    • 2
  1. 1.Department of AnesthesiologyWinona HealthWinonaUSA
  2. 2.Department of AnesthesiologyMayo ClinicRochesterUSA

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