Comfortably Numb

Local anesthetics


This case discusses the additive effects of local anesthetics.


Pharmacodynamics Pharmacokinetic Local anesthetics Mepivacaine Bupivacaine Lidocaine Aminoamide Toxicity Central nervous sytem toxicity Cardiac toxicity Sodium channels α1-glycoprotein Albumin Intralipid Glutamate Hepatic clearance 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of AnesthesiologyUniversity of Pittsburgh Medical CenterPittsburghUSA
  2. 2.Department of AnesthesiologyUniversity of Pittsburgh School of MedicinePittsburghUSA

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