G-computation: Parametric Estimation of Optimal DTRs

  • Bibhas Chakraborty
  • Erica E. M. Moodie
Part of the Statistics for Biology and Health book series (SBH)


In this chapter, we present the fully parametric estimation approach of G-computation, in both frequentist and Bayesian settings. The method is illustrated using an analysis of the Promotion of Breastfeeding Intervention Trial.


Posterior Predictive Distribution Hypothetical Population Marginal Structural Model Counterfactual Outcome Counterfactual Distribution 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Bibhas Chakraborty
    • 1
  • Erica E. M. Moodie
    • 2
  1. 1.Department of BiostatisticsColumbia UniversityNew YorkUSA
  2. 2.Department of Epidemiology, Biostatistics, and Occupational HealthMcGill UniversityMontrealCanada

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