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Anti-Inflammatory Therapeutics in COPD: Past, Present, and Future

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Smoking and Lung Inflammation

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Abstract

Corticosteroids are highly effective in the therapy of asthma; whereas they have little or no anti-inflammatory effects in most patients with COPD. This has prompted a search for alternative anti-inflammatory treatments, and this has so far proved to be a great challenge. The only effective anti- inflammatory treatment for COPD that is in current use is theophylline, which is widely used in developing countries but little use in Western countries because of its side effects at high doses. There is a pressing need to develop new anti-inflammatory treatments in order to more effectively treat systems, prevent exacerbations, reduce disease progression, and reduce mortality.

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Authors and Affiliations

  1. Section of Airway Disease, National Heart and Lung Institute, Imperial College, Dovehouse St, SW3 6LY, London, UK

    Peter J. Barnes

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  1. Peter J. Barnes
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Correspondence to Peter J. Barnes .

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Editors and Affiliations

  1. Center for Inflammation, Temple University School of Medicine, Philadelphia, Pennsylvania, USA

    Thomas J. Rogers

  2. Department of Medicine & Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA

    Gerard J. Criner

  3. Center for Inflammation, Temple University School of Medicine, Philadelphia, Pennsylvania, USA

    William D. Cornwell

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Barnes, P.J. (2013). Anti-Inflammatory Therapeutics in COPD: Past, Present, and Future. In: Rogers, T., Criner, G., Cornwell, W. (eds) Smoking and Lung Inflammation. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7351-0_10

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