Skip to main content
SpringerLink
Log in

Tumor Embolization: Embolization of Liver Tumors

  • Chapter
  • First Online:
Endovascular Interventions

  • 244 Accesses

Abstract

With approximately one million deaths per year, liver cancer is the fourth leading cause of cancer-related deaths worldwide. The disease is, in general, lethal, with the mortality almost equaling its incidence. Hepatocellular carcinoma (HCC) usually arises in the setting of chronic liver disease or cirrhosis and is the most common cause of death in patients with compensated liver cirrhosis. Risks factors for the development of HCC includes hepatitis B carrier state, hepatitis C infection, hereditary hemochromatosis, and cirrhosis. Despite development of different treatment strategy, overall survival rates of HCC remain poor, with estimation of 54 % at 1 year, 40 % at 2 years, and 28 % at 3 years. In patients with late-stage diagnosis, the median survival is between 6 and 20 months.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. El-Serag HB. Hepatocellular carcinoma: an epidemiologic view. J Clin Gastroenterol. 2002;35S:72–8.

    Article  Google Scholar 

  2. Munoz N, Bosch FX. Epidemiology of hepatocellular carcinoma. In: Okuda K, Ishak K, editors. Neoplasms of the liver. Tokyo: Springer; 1989. p. 3–19.

    Google Scholar 

  3. Eattovich G, Stroffolini T, Zagni I, Donato F. Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology. 2004;127(5 Suppl 1):S35–50.

    Article  Google Scholar 

  4. A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients: the Cancer of the Liver Italian Program (CLIP) investigators. Hepatology. 1998;28:751–5.

    Google Scholar 

  5. Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of smallhepatocellular carcinomas in patients with cirrhosis. N Engl J Med. 1996;334:693–9.

    Article  PubMed  CAS  Google Scholar 

  6. Yao FY, Ferrell L, Bass NM, Bacchetti P, Ascher NL, Roberts JP. Livertransplantation for hepatocellular carcinoma: comparison of the proposed UCSF criteria with the Milan criteria and the Pittsburgh modified TNM criteria. Liver Transpl. 2002;8:765–74.

    Article  PubMed  Google Scholar 

  7. Freeman Jr RB. Transplantation for hepatocellular carcinoma: The Milan criteria and beyond. Liver Transpl. 2006;12 Suppl 2:S8–13.

    Article  PubMed  Google Scholar 

  8. Nakamura H, Hashimoto T, Oi H, Sawada S. Transcatheter oily chemoembolization for hepatocellular carcinoma. Radiology. 1989;170:783–6.

    PubMed  CAS  Google Scholar 

  9. Venook AP, Stagg RJ, Lewis BJ, Chase JL, Ring EJ, Maroney TP, et al. Chemoembolization for hepatocellular carcinoma. J Clin Oncol. 1990;8:1108–14.

    PubMed  CAS  Google Scholar 

  10. Bronowicki JP, Vetter D, Dumas F, et al. Transcatheter oily chemoembolization for hepatocellular carcinoma. A four-year study of 127 French patients. Cancer. 1994;74:16–24.

    Article  PubMed  CAS  Google Scholar 

  11. Lammer J, Malagari K, Vogl T, et al. Prospective randomized study of doxorubicin-eluding bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study. Cardiovasc Intervent Radiol. 2010;33:41–52.

    Article  PubMed  Google Scholar 

  12. Inarrairaegui M, Thurston KG, Bilbao JI, et al. Radioembolization with use of Yttrium-90 microspheres in patients with hepatocellular carcinoma and portal vein thrombosis. J Vasc Interv Radiol. 2010;21:1205–12.

    Article  PubMed  Google Scholar 

  13. Llovet JM, Real MI, Montana X, et al. Arterial embolization or chemoembolisation versus symptomatic treatments in patients with unresectable hepatocellular carcinoma: a randomized controlled trial. Lancet. 2002;359:1734–9.

    Article  PubMed  Google Scholar 

  14. Marelli L, Stigliano R, Triantos C, et al. Transarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies. Cardiovasc Intervent Radiol. 2007;30:6–25.

    Article  PubMed  Google Scholar 

  15. Chan AO, Yuen MF, Hui CK, et al. A prospective study regarding the complications of transcatheter arterial lipiodol chemoembolization in patients with hepatocellular carcinoma. Cancer. 2002;94:1747–52.

    Article  PubMed  Google Scholar 

  16. Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008;359:378–90.

    Article  PubMed  CAS  Google Scholar 

  17. Kang SG, Yoon CJ, Jeong SH, et al. Single-session combined therapy with chemoembolization and radiofrequency ablation in hepatocellular carcinoma less than or equal to 5 cm: a preliminary study. J Vasc Interv Radiol. 2009;20:1570–7.

    Article  PubMed  Google Scholar 

  18. Cabibbo G, Latteri F, Antonucci M, Craxi A. Multimodal approaches to the treatment of hepatocellular carcinoma. Nat Clin Pract Gastroenterol Hepatol. 2009;6:159–69.

    Article  PubMed  Google Scholar 

  19. Bruix J, Sherman M. Practice guidelines committee. American Association for the study of liver diseases. Management of hepatocellular carcinoma. J Hepatol. 2005;42:1208–36.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Section of Vascular and Interventional Radiology, Department of Radiology, The University of Chicago Medical Center, 5841 South Maryland Avenue, MC2026, Chicago, IL, 60637, USA

    Thuong G. Van Ha MD

Authors
  1. Thuong G. Van Ha MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Edward Hines, Jr. VA Hospital Loyola University Medical Center, Glen Ellyn, Illinois, USA

    Robert S. Dieter

  2. Northern Illinois Surgery Center, Naperville, Illinois, USA

    Raymond A. Dieter, Jr.

  3. University of Tennessee Medical Center, Knoxville, Tennessee, USA

    Raymond A. Dieter, III

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this chapter

Cite this chapter

Van Ha, T.G. (2014). Tumor Embolization: Embolization of Liver Tumors. In: Dieter, R., Dieter, Jr., R., Dieter, III, R. (eds) Endovascular Interventions. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7312-1_73

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-7312-1_73

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-7311-4

  • Online ISBN: 978-1-4614-7312-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation