CD2-Associated Protein (CD2AP)

Chapter

Abstract

Genome-wide association studies have implicated the cytoplasmic scaffold CD2-associated protein (CD2AP) in Alzheimer’s disease. Although this association requires independent replication, mechanistically it is involved in recognised disease pathways; immune system function and endocytosis. Currently there is little research into the role of CD2AP in healthy or disease brain tissue, which will be essential to translate the genetic data in the future.

Keywords

Albumin Codon Dementia Carboxyl Polypeptide 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Human Genetics, School of Molecular Medical Sciences, Queen’s Medical CentreUniversity of NottinghamNottinghamUK

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