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Pathology of Renal Cell Carcinoma

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Renal Cancer

Abstract

Renal cell carcinomas (RCC) are tumors that arise from the renal tubular epithelium. It encompasses a group of heterogeneous tumors with diverse clinical, pathological, and molecular characteristics as well as distinct prognosis and therapeutic responses. We review the pathological and molecular characteristics of major histological subtypes of RCC that are recognized by the 2004 World Health Organization (WHO) classification of renal tumors. We also discuss several newly described subtypes of RCC and RCC associated with inherited cancer syndromes. The prognostic significance of various histological parameters is also highlighted.

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Authors and Affiliations

  1. Departments of Pathology and Urology, New York University Langone Medical Center, New York, NY, USA

    Fang-Ming Deng M.D., Ph.D. & Jonathan Melamed M.D.

  2. Departments of Pathology and Urology, New York University Langone Medical Center, 560 First Ave, New York, NY, 10016, USA

    Ming Zhou M.D., Ph.D.

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  1. Fang-Ming Deng M.D., Ph.D.
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Correspondence to Ming Zhou M.D., Ph.D. .

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  1. , Institute of Urology, Lahey Clinic, 41 Mall Road, Burlington, 01805, Massachusetts, USA

    John A Libertino

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Deng, FM., Melamed, J., Zhou, M. (2013). Pathology of Renal Cell Carcinoma. In: Libertino, J. (eds) Renal Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7236-0_4

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