Abstract
Proliferations of endothelial cells are relatively common and include malformations and benign, intermediate, or malignant neoplasms. Many arise in the skin, but they also occur in subcutaneous and subfascial soft tissue, and subsets arise in viscera and serosal membranes.
Hemangiomas are benign neoplasms that may be circumscribed; usually have well-formed vessels, a wide variety of patterns, and clinical manifestations; and may be difficult to distinguish from hamartomatous conditions or malformations. Hemangioendotheliomas are mostly of intermediate malignant status, although they sometimes are frankly malignant, and they may be variably vasoformative. Angiosarcomas occur in distinct clinicopathologic settings and are infiltrative rather than circumscribed.
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Fisher, C. (2013). Vascular Lesions. In: Atlas of Soft Tissue Tumor Pathology. Atlas of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7025-0_14
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DOI: https://doi.org/10.1007/978-1-4614-7025-0_14
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