Skeletal Muscle Tumors

  • Cyril Fisher
Part of the Atlas of Anatomic Pathology book series (AAP)


Lesions that differentiate toward skeletal muscle form a distinct subgroup of soft tissue tumors. They include a small number of benign tumors and tumor-like lesions and a clinically more important group of malignant neoplasms: rhabdomyosarcomas. Although they are uncommon overall, rhabdomyosarcomas of embryonal and alveolar types, which are genetically distinct, are the most frequent soft tissue sarcomas of childhood and adolescence. Pleomorphic rhabdomyosarcoma occurs mainly in older adults. Spindle cell rhabdomyosarcoma has two forms: the pediatric type, which is relatively indolent, and the adult type, which is a more aggressive neoplasm.


Germ Cell Tumor Gastrointestinal Stromal Tumor Soft Tissue Tumor Malignant Peripheral Nerve Sheath Tumor Nerve Sheath Tumor 
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© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Cyril Fisher
    • 1
  1. 1.Department of HistopathologyThe Royal Marsden HospitalLondonUK

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