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Radiotherapy for Dermatofibrosarcoma Protuberans

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Radiation Therapy for Skin Cancer

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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare indolent cutaneous tumor; approximately 10–15 % contain areas of fibrosarcoma (DFSP-FS) and tend to behave more aggressively. The optimal treatment is resection with wide margins; the likelihood of local control after this procedure exceeds 90 %. Patients with positive or close margins have a high risk of local recurrence after surgery alone; the addition of postoperative radiotherapy results in local control rates of 85 % or higher. The dose-fractionation schedules are similar to those used for carcinomas. Experience with radiotherapy alone for gross disease is limited. The probability of regional or distant metastases is 5 % or less.

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Authors and Affiliations

  1. Department of Radiation Oncology, College of Medicine, University of Florida, 2000 SW Archer Road, Gainesville, FL, 32610, USA

    William M. Mendenhall

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  1. William M. Mendenhall
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Correspondence to William M. Mendenhall .

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Editors and Affiliations

  1. Florida State University College of Medi, Division of Dermatology, Dermatology Associates of Tallahassee, Riggins Road 1707, Tallahassee, 32308, Florida, USA

    Armand B. Cognetta Jr.

  2. College of Medicine, Department of Radiation Oncology, University of Florida, 2000 SW Archer Road, Gainesville, 32610, Florida, USA

    William M. Mendenhall

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Mendenhall, W.M. (2013). Radiotherapy for Dermatofibrosarcoma Protuberans. In: Cognetta Jr., A., Mendenhall, W. (eds) Radiation Therapy for Skin Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6986-5_16

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  • DOI: https://doi.org/10.1007/978-1-4614-6986-5_16

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  • Online ISBN: 978-1-4614-6986-5

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