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Surgical Treatment for Advanced Heart Failure pp 1–8Cite as

Principles of Heart Failure

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Abstract

This chapter is a review of the epidemiology and physiology of heart failure. As heart failure imposes a significant burden on both the patient and the healthcare system, there is considerable effort to better understand its physiological basis. The chapter first discusses the response of the heart to hemodynamic stress in the healthy state and in heart failure. The chapter then focuses on the causes of heart failure as well as the elements that contribute to its progression. The focus shifts to the body’s defenses to heart failure, which includes a coordination between the heart and kidney and a programmed remodeling response at the cellular level. The chapter concludes with a description of how these compensatory mechanisms may temporize the disease but ultimately serve to worsen heart failure in the long term.

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Author information

Authors and Affiliations

  1. Department of Medicine, New York Presbyterian-Columbia University Medical Center, 622 W. 168th St., New York, NY, 10023, USA

    Benjamin Hirsh M.D.

  2. New York Presbyterian Hospital, Columbia University Medical Center, 622 W. 168th St., PH 12-Stem, New York, NY, 10032, USA

    Ulrich P. Jorde M.D.

Authors
  1. Benjamin Hirsh M.D.
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  2. Ulrich P. Jorde M.D.
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Corresponding author

Correspondence to Benjamin Hirsh M.D. .

Editor information

Editors and Affiliations

  1. Division of Cardiothoracic Surgery, Henry Ford Hospital, West Grand Blvd. 2799, Detroit, 48202, Michigan, USA

    Jeffrey A. Morgan

  2. Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Fort Washington Avenue 177, New York, 10032, New York, USA

    Yoshifumi Naka

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© 2013 Springer Science+Business Media New York

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Hirsh, B., Jorde, U.P. (2013). Principles of Heart Failure. In: Morgan, J., Naka, Y. (eds) Surgical Treatment for Advanced Heart Failure. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6919-3_1

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  • DOI: https://doi.org/10.1007/978-1-4614-6919-3_1

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-6918-6

  • Online ISBN: 978-1-4614-6919-3

  • eBook Packages: MedicineMedicine (R0)

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