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Chromosomal Defects

  • Enid Gilbert-Barness
  • Diane E. Spicer
  • Thora S. Steffensen
Chapter

Abstract

Chromosomal abnormalities represent the largest category of causes of death in humans. Abortuses that have reached a 2-week stage of development are estimated to have a 78 % rate of chromosomal abnormalities; however, this rate declines to 62 % for abortions occurring after the first missed menstrual period but before the 20th week. The proportion of fetuses with chromosomal defects drops continuously, with only 6 % of stillborn infants having a chromosome defect. The frequency of major chromosomal abnormalities in spontaneous abortions, the incidence in live-born infants, and the mechanism of chromosomal defects are discussed in this chapter.

Keywords

Turner Syndrome Klinefelter Syndrome Gonadal Dysgenesis Ridge Count Chromosomal Defect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Enid Gilbert-Barness
    • 1
  • Diane E. Spicer
    • 2
  • Thora S. Steffensen
    • 3
  1. 1.Laboratory Medicine, Pediatrics and Obstetrics and Gynecology Tampa General Hospital Morsani College of MedicineUniversity of South FloridaTampaUSA
  2. 2.Department of Pediatrics-CardiologyUniversity of FloridaValricoUSA
  3. 3.Department of PathologyTampa General HospitalTampaUSA

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