Abstract
Nevus of Ota and nevus of Ito are uncommon sporadic forms of dermal melanocytosis. They may be associated with capillary malformations. In rare cases malignant melanoma may develop in the skin or the uvea. GNAQ mutations have been detected in some. Some degree of lightening can be achieved with lasers.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Sinha S, Cohen PJ, Schwartz RA. Nevus of Ota in children. Cutis. 2008;82:25–9.
Mishima Y, Mevorah B. Nevus Ota and nevus Ito in American Negroes. J Invest Dermatol. 1961;36:133–54.
Sekar S, Kuruvila M, Pai HS. Nevus of Ota: a series of 15 cases. Indian J Dermatol Venereol Leprol. 2008;74:125–7.
Cowan TH, Balistocky M. The nevus of Ota or oculodermal melanocytosis. The ocular changes. Arch Ophthalmol. 1961;65:483–92.
Mukhopadhyay AK. Nevus of ota associated with nevus of Ito. Indian J Dermatol Venereol Leprol. 2004;70:112–3.
Trindade F, Santonja C, Requena L. Bilateral nevus of Ito and nevus spilus in the same patient. J Am Acad Dermatol. 2008;59:S51–2.
Van Raamsdonk CD, Bezrookove V, Green G, et al. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009;457:599–602.
Landau JM, Vergilis-Kalner I, Goldberg LH, Geronemus RG, Friedman PM. Treatment of Nevus of Ota in Fitzpatrick skin type VI with the 1064-nm QS Nd:YAG laser. Lasers Surg Med. 2011;43:65–7.
Zong W, Lin T. A retrospective study on laser treatment of nevus of Ota in Chinese children – a seven-year follow-up. J Cosmet Laser Ther. 2014;16(4):156–60.
Watanabe S, Takahashi H. Treatment of nevus of Ota with the Q-switched ruby laser. N Engl J Med. 1994;331:1745–50.
Kunachak S, Kunachakr S, Sirikulchayanonta V, Leelaudomniti P. Dermabrasion is an effective treatment for acquired bilateral nevus of Ota-like macules. Dermatol Surg. 1996;22:559–62.
Radmanesh M. Naevus of Ota treatment with cryotherapy. J Dermatol Treat. 2001;12:205–9.
Patel BCK, Egan CA, Lucius RW, Gerwels JW, Mamalis N, Anderson RL. Cutaneous malignant melanoma and oculodermal melanocytosis (nevus of Ota): report of a case and review of the literature. J Am Acad Dermatol. 1998;38:862–5.
Wise SR, Capra G, Martin P, Wallace D, Miller C. Malignant melanoma transformation within a nevus of Ito. J Am Acad Dermatol. 2010;62:869–74.
Shields CL, Kaliki S, Livesey M, et al. Association of ocular and oculodermal melanocytosis with the rate of uveal melanoma metastasis: analysis of 7872 consecutive eyes. JAMA Ophthalmol. 2013;131:993–1003.
Moody MN, Landau JM, Vergilis-Kalner IJ, Goldberg LH, Deni M, Friedman PM. 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet laser and 1,550-nm fractionated erbium-doped fiber laser for the treatment of nevus of Ota in Fitzpatrick skin type IV. Dermatol Surg. 2011;37:1163–7.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer Science+Business Media New York
About this chapter
Cite this chapter
Baselga, E. (2015). Nevus of Ota and Nevus of Ito. In: Silverberg, N., Durán-McKinster, C., Tay, YK. (eds) Pediatric Skin of Color. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6654-3_7
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6654-3_7
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-6653-6
Online ISBN: 978-1-4614-6654-3
eBook Packages: MedicineMedicine (R0)