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The Genetics of Pancreatic Cancer Progression

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Molecular Genetics of Pancreatic Cancer

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Abstract

Pancreatic cancer is caused by mutations in specific cancer genes. While these cancer genes are often categorized into those that are inherited versus somatically acquired, they may also be categorized into those that occur during carcinogenesis versus those that accumulate during clonal progression. This newfound approach to understanding pancreatic cancer genetics now opens the door to understanding those events that play a role specifically in progression to metastatic disease.

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Authors and Affiliations

  1. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, 21231, USA

    Christine A. Iacobuzio-Donahue M.D., Ph.D.

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  1. Christine A. Iacobuzio-Donahue M.D., Ph.D.
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Correspondence to Christine A. Iacobuzio-Donahue M.D., Ph.D. .

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Editors and Affiliations

  1. MED CTR ROOM 2922D, TC, University of Michigan, E Medical CTR Drive 1500, Ann Arbor, 48109-0999, Michigan, USA

    Diane M. Simeone

  2. CRB 2/STE 345, Johns Hopkins University, Orleans Street 1550, Baltimore, 21231, Maryland, USA

    Anirban Maitra

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Iacobuzio-Donahue, C.A. (2013). The Genetics of Pancreatic Cancer Progression. In: Simeone, D., Maitra, A. (eds) Molecular Genetics of Pancreatic Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6549-2_8

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