Abstract
Neuromodulation or electrical stimulation of the neural tissue instead of performing lesions is a current trend in neurosurgery. Regarding epilepsy, neuromodulation is currently under intensive research. The field is growing at a fast pace every day. This work has the purpose of reviewing the various targets that have been stimulated in the search of the possibility to control refractory seizures. A consideration is made of how the different targets and patients are selected: seizure outcomes and adverse effects. Targets can be chosen with the idea to interfere with seizure propagation; this is the case of cerebellar, vagal, subthalamic, and thalamic stimulation. Currently, studies are being performed stimulating the epileptic focus. Even though many controversies regarding which is the best target and stimulating parameters still exist, there is no doubt neuromodulation reduces seizures and has the advantage of being reversible and safe.
Keywords
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Velasco, A.L., Velasco, F. (2013). The Role of Neuromodulation in the Treatment of Refractory Epilepsy. In: Rocha, L., Cavalheiro, E. (eds) Pharmacoresistance in Epilepsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6464-8_17
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