Reactive, Metabolic, and Developmental Conditions

  • Shi Wei
  • Gene P. Siegal
Part of the Atlas of Anatomic Pathology book series (AAP)


This chapter covers several nonneoplastic, noninflammatory entities that are reactive, metabolic, or developmental in nature. Osteoarthritis almost exclusively affects weight-bearing joints and remains mostly idiopathic in nature, although frequently it also is a consequence of other conditions involving the joints and synovium. The metabolic and developmental conditions typically involve the skeleton systemically, although they may present as focal lesions (i.e., Paget disease and phosphaturic mesenchymal tumor).


Arthritis Osteoarthritis Synovitis Osteopetrosis 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Shi Wei
    • 1
  • Gene P. Siegal
    • 2
  1. 1.Immunohistochemistry Laboratory UAB HospitalUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.UAB Health System Department of PathologyUniversity of Alabama at BirminghamBirminghamUSA

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